0000000000677438

AUTHOR

G. Cangemi

showing 3 related works from this author

Matrix metalloproteinases production in malignant pleural effusions after talc pleurodesis

2003

SUMMARY In this study we have evaluated the modifications of matrix metalloproteinases (MMPs) in malignant pleural fluids taken from patients suffering from lung cancer and treated with intrapleural talc instillation to induce pleurodesis. Furthermore, we have analysed the variations of some inflammatory mediators (C-reactive protein, α-1 antitrypsin) and of a protein (plasminogen) involved in MMP activation. In all patients the clinical improvement after talc pleurodesis was followed by a reduction in MMP-1, TIMP-1, C-reactive protein, α-1 antitrypsin and plasminogen activity. Furthermore, MMP-9 levels were variable; in fact, in some patients they were high at the beginning of treatment, i…

MalePathologymedicine.medical_specialtyPleural effusionmedicine.medical_treatmentImmunologyMatrix metalloproteinaseTalcStatistics NonparametricClinical StudiesHumansImmunology and AllergyMedicineLung cancerPleurodesisAgedTissue Inhibitor of Metalloproteinase-1business.industryTalc pleurodesisA proteinPlasminogenMiddle Agedmedicine.diseaseMatrix MetalloproteinasesPleural Effusion MalignantC-Reactive ProteinMatrix Metalloproteinase 9Talcalpha 1-AntitrypsinImmunologyPleural fluidFemaleMatrix Metalloproteinase 1businessPleurodesismedicine.drugClinical and Experimental Immunology
researchProduct

CALR MUTATIONS IN SICILIAN ESSENTIAL THROMBOCYTHEMIA AND MYELOFIBROSIS PATIENTS.

2016

Background. Essential thrombocythemia (ET) and primary myelofibrosis (MF) are myeloproliferative neoplasms characterized by the overproduction of mature cells such as platelets (ET) or early bone marrow fibrosis due to scarring induced by highly proliferating myeloid progenitors and pathological stimulation of local fibroblasts (MF). Somatic mutations in CALR gene have recently identified in the majority of JAK2-V617F and MPL negative ET and MF patients. In this study we evaluated the frequency and type of CALR mutations and their clinical and hematological features. Methods. A total of 54 patients, 29 ET and 25 MF patient, was included in this study. All patients were JAK2 V617F and MPL ne…

JAK2 V617FJAK2 V617F; MPL negativeMPL negative
researchProduct

Characterization of the Magnetic Induction Field produced by Secondary Substations

2014

The aim of this paper is to develop a methodology for measuring the magnetic field distribution around the prefabricated secondary substations in vibrated reinforced concrete, as well as the definition of a methodology to determining the maximum value of magnetic induction produced by the substations in correspondence to nominal current of the transformer. As proposed has been developed in conformity with laws and standards and can be applied to active and passive secondary substations. The experimental validation of the proposed methodology, carried out by a measurements campaign whose results are reported, confirms the validity and returns a versatile and simple tool for the verification …

distance of first approximation (DPA).distribution substationfield measurements of magnetic inductionhuman exposureSettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettricifield measurements of magnetic induction human exposure distribution substation distance of first approximation (DPA).Settore ING-INF/07 - Misure Elettriche E Elettroniche
researchProduct