0000000000680035

AUTHOR

S. Romeo

showing 3 related works from this author

IRIDE: Interdisciplinary research infrastructure based on dual electron linacs and lasers

2014

This paper describes the scientific aims and potentials as well as the preliminary technical design of RUDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity "particles factory", based on a combination of high duty cycle radio-frequency superconducting electron linacs and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of sci…

Nuclear and High Energy PhysicsHigh energySC Linac;Neutron source;FEL;Compton source;Advanced accelerators concepts;Particle physicsSettore FIS/07 - FISICA APPLICATA (A BENI CULTURALI AMBIENTALI BIOLOGIA E MEDICINA)Advanced accelerators conceptTechnical designNOAdvanced accelerators conceptsParticle physicSC Linac; FEL; Particle physics; Neutron source; Compton source; Advanced accelerators conceptsInstrumentationFELPhysicsSC LinacSettore FIS/01 - Fisica SperimentaleAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linac; Instrumentation; Nuclear and High Energy PhysicsParticle physicsAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linac; Nuclear and High Energy Physics; InstrumentationCompton sourceNeutron sourceWide fieldSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Dual (category theory)Free Electron LaserAdvanced accelerators concepts Compton source FEL Neutron source Particle physics SC LinacAdvanced accelerators concepts; Compton source; FEL; Neutron source; Particle physics; SC Linacadvanced accelerators concepts; particle physics; sc linac; compton source; fel; neutron sourceneutron sourcefree electron lasersSystems engineeringFactory (object-oriented programming)Free electron laser
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Distinct patterns of Fos immunoreactivity in striatum and hippocampus induced by different kinds of novelty in mice.

2010

In this study the immediate-early gene Fos was used to investigate the response to different novel stimuli in a wide array of brain regions including the hippocampus, the rhinal cortex, the frontal cortex and different components of the striatal complex. Independent groups of CD-1 mice were exposed to three different novelty conditions: (1) novel environment (empty open field); (2) complex novel environment (i.e. open field containing objects); and (3) identity-based detection of novel objects. We observed that a complex novel environment and a knowledge-based novelty modulated Fos levels in both the dorsal and the ventral components of the striatum, while Fos immunoreactivity in the medial…

MaleCognitive NeuroscienceRhinal cortexHippocampusExperimental and Cognitive PsychologyCell CountStriatumEnvironmentMotor ActivityHippocampusOpen fieldTemporal lobeBehavioral NeuroscienceMiceBasal gangliaAnimalsPrefrontal cortexmedial temporal lobe; striatum; prefrontal cortex; object novelty; environmental noveltyNeuronsAnalysis of VarianceBehavior AnimalNoveltyImmunohistochemistryCorpus StriatumPsychologyNeuroscienceProto-Oncogene Proteins c-fosNeurobiology of learning and memory
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Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver

2017

Abstract Background and Aims Nonalcoholic fatty liver disease is epidemiologically associated with hepatic and metabolic disorders. The aim of this study was to examine whether hepatic fat accumulation has a causal role in determining liver damage and insulin resistance. Methods We performed a Mendelian randomization analysis using risk alleles in PNPLA3, TM6SF2, GCKR and MBOAT7, and a polygenic risk score for hepatic fat, as instruments. We evaluated complementary cohorts of at‐risk individuals and individuals from the general population: 1515 from the liver biopsy cohort (LBC), 3329 from the Swedish Obese Subjects Study (SOS) and 4570 from the population‐based Dallas Heart Study (DHS). Re…

AdultGenetic MarkersLiver CirrhosisMalenonalcoholic fatty liver diseaseNon-alcoholic Fatty Liver Diseaseinsulin resistanceHumansgeneticsProspective StudiesAdaptor Proteins Signal TransducingSettore MED/12 - GastroenterologiafibrosisMembrane ProteinsOriginal ArticlesLipaseMendelian Randomization AnalysisAdipose TissueDiabetes Mellitus Type 2Chronic Diseasemendelian randomizationOriginal ArticleFemaletype 2 diabetesgeneticfibrosiAcyltransferases
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