0000000000681160

AUTHOR

María Marcela López

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Mucositis and salivary antioxidants in patients undergoing bone marrow transplantation (BMT)

2014

Objectives: High doses of chemotherapy generate DNA damage in patients undergoing bone marrow transplantation (BMT), due to the production of reactive oxygen species (ROS). In order to evaluate the local defensive effectiveness of the patient undergoing BMT, the concentrations of the antioxidants superoxide dismutase (SOD) and uric acid (UA) were measured in saliva. Study Design: Basal saliva samples were collected from 20 patients undergoing BMT at the Oncology Depart- ment, Sanatorio Allende (Córdoba), in the stages: initial, prior to conditioning therapy (I); middle: 7 to 10 days after BMT (M) and final stage, 30 days after discharge from isolation (F). SOD levels were determined using a…

MaleSalivaPathologymedicine.medical_treatmentmedicine.disease_causeGastroenterologychemistry.chemical_compoundBasal (phylogenetics)Postoperative ComplicationsLongitudinal StudiesBone Marrow Transplantationchemistry.chemical_classificationbiology//purl.org/becyt/ford/3.1 [https]Middle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMedicina BásicaUNESCO::CIENCIAS MÉDICASFemale//purl.org/becyt/ford/3 [https]AdultMucositismedicine.medical_specialtyCIENCIAS MÉDICAS Y DE LA SALUDOdontologíaFisiologíaSuperoxide dismutaseInternal medicinemedicineMucositisHumansSalivaGeneral DentistryAgedReactive oxygen speciesChemotherapyOral Medicine and Pathologybusiness.industrySuperoxide DismutaseResearchmedicine.diseaseUric AcidOtorhinolaryngologychemistrybiology.proteinUric acidSurgerybusinessOxidative stress
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