0000000000690063

AUTHOR

Juan Carlos Navarro

showing 13 related works from this author

Aquatic pollution may favor the success of the invasive species A. franciscana

2015

The genus Artemia consists of several bisexual and parthenogenetic sibling species. One of them, A. franciscana, originally restricted to the New World, becomes invasive when introduced into ecosystems out of its natural range of distribution. Invasiveness is anthropically favored by the use of cryptobiotic eggs in the aquaculture and pet trade. The mechanisms of out-competition of the autochthonous Artemia by the invader are still poorly understood. Ecological fitness may play a pivotal role, but other underlying biotic and abiotic factors may contribute. Since the presence of toxicants in hypersaline aquatic ecosystems has been documented, our aim here is to study the potential role of an…

Health Toxicology and Mutagenesismedia_common.quotation_subjectDrug ResistanceAquatic ScienceBiologyCompetition (biology)Invasive specieschemistry.chemical_compoundSpecies SpecificityInvasionLife tablesAnimalsmedia_commonAbiotic componentResistance (ecology)ToxicityEcologyAquatic animalFecunditychemistryChlorpyrifosAChEChlorpyrifosArtemiaIntroduced SpeciesWater Pollutants ChemicalToxicantAquatic toxicology 161: 208-220 (2015)
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Proteomic evaluation of potentiated sulfa treatment on gilthead sea bream (Sparus aurata L.) liver

2013

Potentiated sulfa drugs are a combination of sulfonamide and pyrimidine potentiators. They are currently used against fish bacterial pathogens in Mediterranean marine fish farming. The present work aimed studying the potential hepatotoxicity of a combination of sulfadiazine (SDZ) and trimethoprim (TMP) in gilthead sea bream juveniles after oral administration, at the recommended ratio of 5: 1 (SDZ/TMP), equivalent to a dose of 30 mg kg(-1) fish day(-1), for 10 days at 19 degrees C temperature. Electrophoresis (DIGE) technology coupled with MS was used to identify possible markers of hepatotoxicity of this treatment. The results obtained show significant changes in the expression of 41 prote…

AntioxidantApolipoprotein Bbiologymedicine.medical_treatmentFish farmingLipid metabolismAquatic ScienceCarbohydrate metabolismFatty acid-binding proteinSulfadiazineBiochemistrybiology.proteinmedicineProtein biosynthesismedicine.drug
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Effects of ibuprofen and carbamazepine on the ion transport system and fatty acid metabolism of temperature conditioned juveniles of Solea senegalens…

2018

The increasing presence of pharmaceuticals in aquatic environments in the last decades, derived from human and veterinary use, has become an important environmental problem. Previous studies have shown that ibuprofen (IB) and carbamazepine (CBZ) modify physiological and biochemical processes in Senegalese sole (Solea senegalensis) in a temperature-dependent manner. In other vertebrates, there is evidence that both of these pharmaceuticals interfere with the ‘arachidonic acid (AA) cascade’, which is responsible for the biosynthesis of numerous enzymes that are involved in the osmoregulatory process. The present work aims to study the temperature-dependent effects of these two pharmaceuticals…

0301 basic medicineGillGillsHealth Toxicology and MutagenesisATPaseAcclimatizationIbuprofen010501 environmental sciencesKidney01 natural scienceschemistry.chemical_compoundOsmoregulationProtein IsoformsIntestinal MucosaNa+ K+ -ATPasebiologyFatty AcidsTemperatureGeneral MedicineWater-Electrolyte BalancePollutionEicosapentaenoic acidIntestinesCarbamazepineBiochemistryOsmoregulationFlatfishesPharmaceuticalsArachidonic acidSodium-Potassium-Exchanging ATPasemedicine.medical_specialtyBiochemical Phenomena03 medical and health sciencesInternal medicinemedicineAnimalsNa+/K+-ATPaseFatty acids0105 earth and related environmental sciencesIon TransportFatty acid metabolismMarinePublic Health Environmental and Occupational HealthLipid MetabolismEnzyme assay030104 developmental biologyEndocrinologyFishchemistryProstaglandin-Endoperoxide Synthasesbiology.proteinWater Pollutants ChemicalEcotoxicology and environmental safety
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The Constant Threat of Zoonotic and Vector-Borne Emerging Tropical Diseases: Living on the Edge

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)emergingSARS-CoV-2/COVID-2challengesGeneral MedicineTropical DiseasesVirologyGeographyVector (epidemiology)vector-borne diseasesEnhanced Data Rates for GSM Evolutionzoonotic diseasesConstant (mathematics)Specialty Grand ChallengeFrontiers in Tropical Diseases
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Effect of virgin low density polyethylene microplastic ingestion on intestinal histopathology and microbiota of gilthead sea bream

2021

© 2021 The Authors.

NecrosisbiologyIngestionMicrobiotaMicroplasticPhysiologyHistopathologyInflammationAquatic ScienceGut florabiology.organism_classificationmedicine.diseaseMucusDesquamationVacuolizationSparus auratamedicineIngestionmedicine.symptomDysbiosis
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Effect of sublethal concentrations of copper sulphate on seabreamSparus auratafingerlings

2007

The gilthead seabream is the most important Mediterranean aquacultured fish species. The main objective of this study was to investigate whether copper sulphate bath treatments used routinely in aquaculture have effects on important physiological functions of early life stages of the gilthead seabream (Sparus aurata). Fingerlings (80-90 days, 0.27 ± 0.06 g) were exposed to copper sulphate baths at 0, 0.25, 0.5 and 1.5 mg L −1 during 24 h. Effects on the central nervous function were evaluated analysing brain acetylcholinesterase activity (AChE). Oxidative stress was assessed by the quantification of lipid peroxidation (LP). Heat shock proteins (HSP70) were used as a general response to chem…

SparidaeAchéPhysiological conditionAquatic ScienceBiologymedicine.disease_causebiology.organism_classificationAcetylcholinesteraselanguage.human_languageHsp70Lipid peroxidationchemistry.chemical_compoundchemistryBiochemistryHeat shock proteinlanguagemedicineOxidative stressAquatic Living Resources
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Effect of ivermectin on the liver of gilthead sea bream Sparus aurata: a proteomic approach.

2010

23 p., 2 tablas, 4 figuras y bibliografía

ProteomicsFish ProteinsEnvironmental EngineeringNew biomarkersSparidaeProteomeHealth Toxicology and MutagenesisDifference gel electrophoresisBiologyIvermectinAquaculturemedicineEnvironmental ChemistryAnimalsGilthead seabreamIvermectinAntiparasitic AgentsEcologybusiness.industryPublic Health Environmental and Occupational HealthHepatotoxinLipid metabolismAquatic animalGeneral MedicineGeneral ChemistryMetabolismbiology.organism_classificationPollutionSea BreamMass spectrometry (MS)BiochemistryLiver2D-DIGEbusinessBiomarkersWater Pollutants Chemicalmedicine.drugChemosphere
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Effects of dichlorvos aquaculture treatments on selected biomarkers of gilthead sea bream (Sparus aurata L.) fingerlings

2007

Abstract The gilthead sea bream ( Sparus aurata ) is the most important marine cultured species in the Mediterranean. Dichlorvos is one of the main chemical agents used in bath treatments against ectoparasites of marine farmed fish. The main objective of this study was to investigate the effects of 24 h dichlorvos baths on selected biomarkers that are involved in important physiological functions or indicative of gilthead sea bream fingerlings growth. To attain this objective, the in vivo effects of dichlorvos on cholinesterases' activity (ChE), lipid peroxidation (TBARS), RNA/DNA ratio, glutathione S -transferases activity (GST) and heat shock proteins HSP70 were studied. The characterizat…

Sparidaebusiness.industryFish farmingGlutathioneAquatic ScienceBiologybiology.organism_classificationHsp70Lipid peroxidationchemistry.chemical_compoundAquaculturechemistryBiochemistryDichlorvosTBARSbusinessAquaculture
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Acute toxicity of dichlorvos to Aphanius iberus (Cuvier & Valenciennes, 1846) and its anti-cholinesterase effects on this species

2008

This study evaluates the toxic effects of the organophosphate pesticide (OP) dichlorvos to the endangered Iberian toothcarp (Aphanius iberus). To this end, the lethal toxicity of dichlorvos based on 96 h-LC50 bioassays was determined in saline water (50 g/L), and in vivo effects of dichlorvos on cholinesterase (ChE) activity were investigated in adult female and male specimens. The 96 h-LC50 value determined by probit analysis was 3.17 mg/L (95% confidence limits: 1.34-3.97). The characterisation of the ChE using different substrates and specific inhibitors was also carried out in head and muscle tissues. Acetylthiocholine was the substrate preferred by both head and muscle ChE in males and…

Malemedicine.medical_specialtyAchéHealth Toxicology and MutagenesisAquatic ScienceToxicologychemistry.chemical_compoundInternal medicineDichlorvosmedicineAnimalsCholinesterasesCholinesterase (ChE)Cholinesterasebiologyintegumentary systemToxicityKillifishesMusclesOrganophosphateAcetylcholinesteraseSurvival AnalysisAcute toxicitylanguage.human_languageEnzyme assayEndocrinologyFishchemistryAphaniusToxicityDichlorvosbiology.proteinlanguageFemaleCholinesterase InhibitorsWater Pollutants ChemicalBiomarkers
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Assessment of the efficacy of Artemia sp (Crustacea) cysts chorion as barrier to chlorpyrifos (organophosphorus pesticide) exposure. Effect on hatchi…

2005

In order to reveal the efficacy of the Artemia cysts chorion as barrier to the organophosphorus pesticide chlorpyrifos, whole and decapsulated cysts have been exposed to 10 mg L(-1) chlorpyrifos in sea water during hydration and hatching phase, separately. The concentration of chlorpyrifos in capsulated and decapsulated cysts after exposure has been determined in order to elucidate the efficacy of chorion as protection to the embryo. The results obtained demonstrate the ability of the cysts chorion to obstruct the pass of chlorpyrifos molecules through this protection structure. Thus, the concentration of chlorpyrifos in exposed decapsulated cysts is higher than in exposed whole cysts. More…

Food ChainTime Factorsanimal structuresEnvironmental EngineeringAndrologyToxicologychemistry.chemical_compoundOrganophosphorus CompoundsCrustaceaparasitic diseasesAnimalsEnvironmental ChemistrySeawaterPesticidesWaste Management and DisposalLarvabiologyHatchingFishesEmbryoPesticidebiology.organism_classificationPollutionCrustaceanSurvival RatechemistryLarvaChlorpyrifosembryonic structuresArtemia sp.ChlorpyrifosOrganophosphorus pesticidesWater Pollutants ChemicalEnvironmental MonitoringScience of The Total Environment
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Editorial: Emerging Zoonoses: Eco-Epidemiology, Involved Mechanisms, and Public Health Implications

2015

Zoonoses are currently considered as one of the most important threats for Public Health worldwide. Zoonoses can be defined as any disease or infection that is naturally transmissible from vertebrate or invertebrate animals to humans and vice-versa. Approximately, 75% of recently emerging infectious diseases affecting humans are diseases of animal origin; approximately, 60% of all human pathogens are zoonotic. All types of potential pathogenic agents, including viruses, parasites, bacteria, and fungi, can cause these zoonotic infections. From the wide range of potential vectors of zoonoses, arthropods are probably those of major significance due to their abundance, high plasticity, adaptabi…

Veterinary medicineZoonotic InfectioneditorialPublic Health Environmental and Occupational HealthZoologyHuman pathogenDiseaseBiologymedicine.diseaseinfectious diseasesPopulation controlDengue feverzoonosesone healthOne Healthinfectious diseases epidemiologymedicineVector (molecular biology)Public HealthMalariaFrontiers in Public Health
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Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region

2019

In the past 5–10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has be…

Chagas diseaseDisease transmissionSeroprevalenceReviewmedicine.disease_causeCommunicable Diseases EmergingBOLIVAR STATEZika virusZika virusCHIKUNGUNYADengue0302 clinical medicineInfection preventionINFECTIONSIFONTES030212 general & internal medicineChikungunyaGeography MedicalMAYAROChildSocioeconomicsLeishmaniasisPriority journalArbovirusbiologyTransmission (medicine)Incidence (epidemiology)IncidencePoliticsOilParasite incidenceInfectious DiseasesGeographyVIRUSInfectiongeographic locationsHumanAdultmedicine.medical_specialtyanimal structuresAdolescentCHAGAS-DISEASETrypanosoma cruzi030231 tropical medicineHumanitarian crisisEpidemicVector Borne DiseasesDisease elimination03 medical and health sciencesMALARIAHUMANITARIAN CRISISEPIDEMICparasitic diseasesmedicineSeroprevalenceAnimalsHumansEpidemicsAgedMUNICIPALITYPublic healthDisease re-emergenceNonhumanmedicine.diseasebiology.organism_classificationVenezuelaMalariaEconomic aspectDisease carrierCommunicable Disease ControlChikungunyaMalariaLancet Infectious Diseases
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SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

2021

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 da…

Malepulmonary embolismInternationalitySettore MED/18 - CHIRURGIA GENERALEDeep veinVascular damage Radboud Institute for Health Sciences [Radboudumc 16]infectious diseasesCardiovascularSARS‐CoV‐2surgeryCOVID-19 ; SARS-CoV-2 ; deep vein thrombosis ; pulmonary embolism ; venous thromboembolismCohort StudiesPostoperative ComplicationsAnesthesiologyMedicine and Health SciencesProspective Studies610 Medicine & healthProspective cohort studyLung11 Medical and Health SciencesConfoundingHematologyMiddle AgedThrombosis17 Psychology and Cognitive SciencesCOVID-19; deep vein thrombosis; pulmonary embolism; SARS-CoV-2; venous thromboembolismPulmonary embolismCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolism.medicine.anatomical_structureCohortCOVID-19/complicationsPostoperative Complications/etiologyOriginal ArticleFemalePatient SafetyLife Sciences & BiomedicineCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolismHumanAdultmedicine.medical_specialtyAdolescentClinical Sciencesvenous thromboembolism610 Medicine & healthGlobalSurg CollaborativeVenous Thromboembolism/etiologydeep vein thrombosisNOCOVIDSurg CollaborativeYoung AdultMedicine General & InternalAge DistributionClinical ResearchCOVID‐19General & Internal MedicinemedicineHumansSex DistributionAgedScience & Technologybusiness.industrySARS-CoV-2PreventionNeurosciencesdeep vein thrombosiCOVID-19PneumoniaOdds ratioOriginal Articlesmedicine.diseaseSurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Prospective StudieGood Health and Well BeingAnesthesiology and Pain MedicineHuman medicinePostoperative ComplicationCohort StudiebusinessVenous thromboembolism[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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