0000000000697033

AUTHOR

Kay Nolte

showing 2 related works from this author

Nuclear actin aggregation is a hallmark of anti-synthetase syndrome-induced dysimmune myopathy

2015

Objective: To analyze antisynthetase syndrome–associated myositis by modern myopathologic methods and to define its place in the spectrum of idiopathic inflammatory myopathies (IIMs). Methods: Skeletal muscle biopsies from antisynthetase syndrome–associated myositis and other IIMs from different institutions worldwide were analyzed by histopathology, quantitative PCR, and electron microscopy. Results: Myonuclear actin filament inclusions were identified as a unique morphologic hallmark of antisynthetase syndrome–associated myositis. Nuclear actin inclusions were never found in dermatomyositis, polymyositis, sporadic inclusion body myositis, autoimmune necrotizing myopathy associated with si…

Pathologymedicine.medical_specialtyBiopsyIntranuclear Inclusion Bodies10208 Institute of Neuropathology610 Medicine & healthAntisynthetase syndromeBiologyPolymyositisSensitivity and SpecificityNecrosisPerimysialmedicineHumansMyopathyMuscle SkeletalMyositisMyositisDermatomyositisActin cytoskeletonmedicine.diseaseAutoimmune necrotizing myopathyActins10040 Clinic for NeurologyActin Cytoskeleton2728 Neurology (clinical)Immunology570 Life sciences; biologyNeurology (clinical)medicine.symptom
researchProduct

Long Term Outcome after Application of the Angio-Seal Vascular Closure Device in Minipigs

2016

PLoS one 11(9), e0163878 (2016). doi:10.1371/journal.pone.0163878

SwineAnticoagulant Therapylcsh:MedicineFemoral artery030204 cardiovascular system & hematologyPathology and Laboratory Medicine030218 nuclear medicine & medical imagingWhite Blood Cells0302 clinical medicinePig ModelsAnimal CellsMedicine and Health SciencesVascular closure deviceLymphocyteslcsh:ScienceComputed tomography angiographyMammalsStenosisMultidisciplinarymedicine.diagnostic_testPharmaceuticsAgricultureArteriesAnimal ModelsClopidogrelCardiovascular Therapymedicine.anatomical_structureVertebratesAnatomyCellular TypesArterymedicine.drugResearch Articlemedicine.medical_specialtyLivestockImmune CellsAnimal TypesImmunologyLumen (anatomy)Research and Analysis Methods03 medical and health sciencesSigns and SymptomsModel OrganismsDrug TherapyDiagnostic Medicinemedicine.arterymedicineAnimalsDomestic AnimalsBlood Cellsbusiness.industrylcsh:ROrganismsBiology and Life SciencesCell BiologyFemoral ArteriesInternal elastic laminamedicine.diseaseSurgeryStenosisAmniotesCardiovascular AnatomyBlood Vesselslcsh:QbusinessZoologyPLoS ONE
researchProduct