0000000000700998

AUTHOR

Jianghong He

showing 2 related works from this author

Combined Behavioral and Mismatch Negativity Evidence for the Effects of Long-Lasting High-Definition tDCS in Disorders of Consciousness: A Pilot Study

2020

Objective: To evaluate the effects of long-term High-definition transcranial direct current stimulation (HD-tDCS) over precuneus on the level of consciousness (LOC) and the relationship between Mismatch negativity (MMN) and the LOC over the therapy period in patients with Disorders of consciousness (DOCs). Methods: We employed a with-in group repeated measures design with an anode HD-tDCS protocol (2 mA, 20 min, the precuneus) on 11 (2 vegetative state and nine minimally conscious state) patients with DOCs. MMN and Coma Recovery Scale-Revised (CRS-R) scores were measured at four time points: before the treatment of HD-tDCS (T0), after a single session of HD-tDCS (T1), after the treatment of…

medicine.medical_specialtymedicine.medical_treatmentPrecuneusMismatch negativityDisorders of consciousnessAudiologyevent-related potentialsbehavioral disciplines and activities050105 experimental psychologylcsh:RC321-57103 medical and health sciences0302 clinical medicineLevel of consciousnessmedicine0501 psychology and cognitive scienceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOddball paradigmOriginal ResearchTranscranial direct-current stimulationbusiness.industryGeneral Neuroscience05 social sciencesMinimally conscious stateRepeated measures designmedicine.diseasedisorder of consciousnesskoomamedicine.anatomical_structuremismatch negativitytajunnan tasostimulointihigh-definition transcranial direct current stimulationpoikkeavuusnegatiivisuuscoma recovery scale-revisedbusinesspsychological phenomena and processes030217 neurology & neurosurgeryNeuroscienceFrontiers in Neuroscience
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Spatial Properties of Mismatch Negativity in Patients with Disorders of Consciousness

2018

In recent decades, event-related potentials have been used for the clinical electrophysiological assessment of patients with disorders of consciousness (DOCs). In this paper, an oddball paradigm with two types of frequencydeviant stimulus (standard stimuli were pure tones of 1000 Hz; small deviant stimuli were pure tones of 1050 Hz; large deviant stimuli were pure tones of 1200 Hz) was applied to elicit mismatch negativity (MMN) in 30 patients with DOCs diagnosed using the JFK Coma Recovery ScaleRevised (CRS-R). The results showed that the peak amplitudes of MMN elicited by both large and small deviant stimuli were significantly different from baseline. In terms of the spatial properties of…

MaleMismatch negativityPhysiologyMismatch negativityNeuropsychological TestsAudiologyElectroencephalographySeverity of Illness Indexvegetative stateCorrelation0302 clinical medicineLevel of consciousnessDisorder of consciousnessEEGEvoked PotentialsOddball paradigmMinimally conscious stateVegetative statemedicine.diagnostic_testGeneral Neuroscience05 social sciencesMinimally conscious stateElectroencephalographyGeneral MedicineMiddle Agedtajuttomuusdisorder of consciousnessAuditory PerceptionConsciousness DisordersOriginal ArticleFemalePsychologyAdultmedicine.medical_specialtyAdolescentWavelet AnalysisStimulus (physiology)behavioral disciplines and activities050105 experimental psychology03 medical and health sciencesmedicineHumans0501 psychology and cognitive sciencesAgedmedicine.diseaseminimally conscious stateElectrophysiologyAcoustic StimulationBrain Injuriestajunnan tasopoikkeavuusnegatiivisuus030217 neurology & neurosurgery
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