0000000000701325
AUTHOR
Lee W
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia
Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in patients with thrombocytopenia and chronic liver disease who are undergoing an elective invasive procedure.We randomly assigned 292 patients with chronic liver disease of diverse causes and platelet counts of less than 50,000 per cubic millimeter to receive eltrombopag, at a dose of 75 mg daily, or placebo for 14 days before a planned elective invasive procedure that was performed within 5 days after the last dose. The primary end point was the avoidance of a platelet transfusion before, during, and up to 7…
AGING IN PLACE WITH INTELLECTUAL DISABILITY: CARE TRANSITIONS AMONG OLDER TWO-GENERATION FAMILIES
Little is known of transitions in care and housing of old two-generation families that include aging (≥40) adults with intellectual disability (ID) and their older (≥65) parents. This study employed the “housing pathways” theory in order to explore the experiences of these families of such transitions. All potential old two-generation families from two local authorities in Taiwan were recruited; 237 families completed our survey and 61 our in-depth interviews between May 2015 and July 2016. Different models and types of transitions in care and housing of these families were identified and found to be connected with changes in their care responsibilities and living arrangements. Old parents …
Outcomes of a new residential scheme for adults with intellectual disabilities in Taiwan: a 2-year follow-up
Background The Taiwanese government launched a new programme in November 2004 to support adults with intellectual disabilities living in smaller facilities. This paper aims to evaluate the service outcomes of this new residential scheme over 2 years including those residents who moved from an institution and those who moved from their family. Methods A one-group repeated-measures analysis was conducted for five interviews after the adults with intellectual disabilities entered the new environment. Forty-nine adults were initially studied (T1) and 29 adults remained in the homes until the end of the study (T5). Results This study found significant improvements over the 2 years in the resi…