0000000000701535
AUTHOR
Laura Jones
Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries
Importance: Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events. Objective: To evaluate the incidence and nature of adverse peri-intubation events and to assess current practice of intubation in critically ill patients. Design, Setting, and Participants: The International Observational Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients (INTUBE) study was an international, multicenter, prospective cohort study involving consecutive critically ill patients undergoing tracheal intubation in the intensive care units (ICUs…
Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease
OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need fo…
Using pollen DNA metabarcoding to investigate the foraging preferences of honey bees
Honey bees contribute to human wellbeing; through the use of honey, wax and propolis, and as the pollinator of both wild and crop plants. The increased rate of honey bee colony loss has caused worldwide concern, caused by the interacting effects of habitat loss and fragmentation, agrochemicals, pests and diseases, and climate change. DNA metabarcoding provides a tool for identifying the pollen in honey and therefore the plants the honey bees are foraging upon. The DNA is amplified using the rbcL marker using a two-step protocol and sequenced on the Illumina MiSeq platform. Sequences are compared to our Barcode UK reference library using BLAST. Using the National Botanic Garden of Wales as o…