0000000000703120
AUTHOR
A Nicolosi
showing 3 related works from this author
Indagini genetiche e trattamenti prenatali in utero della Sindrome Adreno Genitale (SAG) in una Coorte Siciliana.
2008
La deficienza dell'enzima 21 idrossilasi (21OHD) è la causa più comune di sindrome adrenogenitale (SAG). Il gene implicato è il CYP21 (6p21.3). La SAG è un problema clinico-sociale in quanto nel 95% dei casi genera l'iperandrogenismo dei neonati di sesso femminile. Il trattamento più effettuato in corso di virilizzazzione dei genitali femminili esterni è di tipo chirurgico (genitoplastica). Il trattamento prenatale in utero è una alternativa medica con il fine di compensare il difetto enzimatico e prevenire l'eccesso di androgeni in corso di morfogenesi fetale. Un nuovo protocollo diagnostico-terapeutico prenatale è stato sviluppato sulla base di una terapia precoce (alla 5° WG) con Desamet…
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.
2019
Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (pro…
Effect of sheep wool fibres on thermal-insulation and mechanical properties of cement matrix
2015
The use of sheep wool as reinforcement of cement in order to produce mortar or plaster involves several advantages for environment and energy. Moreover, in several regions it is treated as a waste and, consequently, its employ is characterized by low cost. Aim of this paper is to evaluate the influence of wool fibres on thermal conductivity and mechanical properties of cement. The samples were prepared using wool fibres, obtained from a breed of Sicilian sheep, with three different length (i.e. 1 mm, 6 mm and 20 mm). Moreover, in order to evaluate the influence of fibre content, the samples were prepared by varying the fibres weight fraction up to maximum level. The thermal conductivity of …