0000000000703754

AUTHOR

Moufida Saidani Tounsi

showing 4 related works from this author

Tunisian grape seed extracts decrease LPS-induced inflammation in murine macrophages

2016

IF 4.066; International audience

Inflammation[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO][ SDV.MHEP.PHY ] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO][SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Murine macrophages
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Does unsaponifiable fraction of grape seed oil attenuate nitric oxide production, oxidant and cytotoxicity activities.

2019

Triterpenoids, tocopherols, and phytosterols presented in unsaponifiable fraction of grape seed oil have several beneficial effects comprising antioxidant, anti-inflammatory, and antitumor capacities. In this study, the unsaponifiable fraction of three Tunisian grape seed varieties (Vitis vinifera L.), namely Merlot, Carignan, and Syrah, was investigated. The identified compounds were two triterpenic compounds (β-amyrin, lanosterol), six phytosterols (campesterol, ∆7 -avenasterol, stigmasterol, β-sitosterol, β-sitostanol, cholesterol), and three tocopherols (α, β, and γ tocopherols). The unsaponifiable fraction had significant protection against oxidative damage by modulating NO production …

Antioxidantfood.ingredient030309 nutrition & dieteticsCell SurvivalCampesterolmedicine.medical_treatmentBiophysicsFraction (chemistry)AvenasterolNitric OxideGrape seed oil03 medical and health scienceschemistry.chemical_compoundMice0404 agricultural biotechnologyfoodmedicineAnimalsVitisFood sciencePharmacology0303 health sciencesStigmasterolGrape Seed ExtractMacrophagesfood and beverages04 agricultural and veterinary sciencesCell BiologyOxidants040401 food scienceRAW 264.7 CellschemistryUnsaponifiableComposition (visual arts)BiomarkersFood ScienceJournal of food biochemistry
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Biochemical characterization and antioxidant activity of grape ( Vitis vinifera L.) seed oils from nine Tunisian varieties

2018

IF 1.552; International audience

0301 basic medicinePharmacology030109 nutrition & dieteticsAntioxidantChemistrymedicine.medical_treatmentBiophysics04 agricultural and veterinary sciencesCell Biology040401 food science03 medical and health scienceschemistry.chemical_compoundHorticulture0404 agricultural biotechnologyTriterpenoidmedicine[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPhenolsVitis vinifera[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Science
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Protective effects of polyphenol-rich infusions from carob (Ceratonia siliqua) leaves and cladodes of Opuntia ficus-indica against inflammation assoc…

2017

IF 2.759; International audience; In the present study, we have investigated the effects of polyphenol-rich infusions from carob leaves and OFI-cladodes on inflammation associated with obesity and dextran sulfate sodium (DSS)-induced ulcerative colitis in Swiss mice. In vitro studies revealed that aqueous extracts of carob leaves and OFI-cladodes exhibited anti-inflammatory properties marked by the inhibition of IL-6, TNF-α and nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells concomitant with NF-κβ nucleus translocation inhibition. For in vivo investigations, Swiss male mice were subjected to control or high fat diet (HFD). At the 8th week after the start …

0301 basic medicineMaleDSS colitisCarob leavesAdipose tissueInflammationBiologyPharmacologyDiet High-FatGalactansHFD obesityNitric oxideCell LineMannans03 medical and health scienceschemistry.chemical_compoundMicefoodSwiss micePlant GumsmedicineAnimalsObesityColitisAcute colitisPharmacologyInflammationIntestinal permeabilityOFI-CladodesDose-Response Relationship DrugDextran Sulfate[ SDV.SP.PHARMA ] Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyOpuntiaPolyphenolsFabaceaeGeneral Medicinemedicine.diseaseColitisUlcerative colitisfood.food3. Good healthPlant LeavesCeratonia siliquaAqueous extract030104 developmental biologychemistry[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacologymedicine.symptomInflammation MediatorsBiomedicinepharmacotherapy = Biomedecinepharmacotherapie
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