0000000000704247

AUTHOR

Zane Kalnin̨a

showing 2 related works from this author

Thermal, glass-forming, nonlinear optical and holographic properties of "push-pull" type azochromophores with triphenyl moieties containing isophoren…

2013

Molecular organic compounds with electron donating fragment bounded through π-conjugated system with electron acceptor fragment, as well as with incorporated triphenyl groups in their molecules show potential for creating cheap and simple solution processable materials with nonlinear optical properties. Additional insertion of azobenzene fragment in their structures makes them also possible to form holographic volume and surface relief gratings (SRG) after exposure to laser radiation, which could be useful for holographic data storage. For these purposes polymers are generally used. However, their application is complicated and challenging task as in every attempt to obtain the same polymer…

chemistry.chemical_classificationDiffractionMaterials sciencebusiness.industryPolymerHolographic data storageDiffraction efficiencyAmorphous solidchemistry.chemical_compoundchemistryAzobenzeneOptoelectronicsPhysical chemistryThermal stabilitybusinessGlass transitionSPIE Proceedings
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Alterations of pre-mRNA splicing in cancer

2005

Recent genomewide analyses of alternative splicing (AS) indicate that up to 70% of human genes may have alternative splice forms, suggesting that AS together with various posttranslational modifications plays a major role in the production of proteome complexity. Splice-site selection under normal physiological conditions is regulated in the developmental stage in a tissue type-specific manner by changing the concentrations and the activity of splicing regulatory proteins. Whereas spliceosomal errors resulting in the production of aberrant transcripts rarely occur in normal cells, they seem to be an intrinsic property of cancer cells. Changes in splice-site selection have been observed in v…

GeneticsCancer ResearchRNA SplicingAlternative splicingExonic splicing enhancerIntronExonsBiologymedicine.disease_causeIntronsCell biologyExonTumor progressionRNA splicingRNA PrecursorsGeneticsmedicineHumansspliceCarcinogenesisGenes, Chromosomes and Cancer
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