Peritumoral perfusion and proton spectroscopic MR imaging in the differentiation of gliomas and solitary metastases

Purpose: To asses the value of peritumoural perfusion-weighted and proton spectroscopic MR imaging in preoperative grading of gliomas and in differentiating between primary gliomas and solitary metastases. Methods and Materials: Ten low-grade gliomas, eight high-grade gliomas, and ten metastases were prospectively evaluated with MR imaging, dynamic susceptibility contrast-enhanced perfusion imaging, and single-voxel proton MR spectroscopy before surgical resection or stereotactic biopsy. Maximal rCBV values and maximal Cho/Cr ratios were calculated from peritumoural region surrounding the tumour. Tumour grade presumed with these values was compared to histopathologic grading. Differences in…

CONTRIBUTO DELLA RM PERFUSIONALE IN ASSOCIAZIONE ALLA SPETTROSCOPIA RM SINGLE VOXEL NELLA DEFINIZIONE DEL GRADING DEI GLIOMI CEREBRALI.

High-­grade gliomas and solitary metastases: differentiation by using peritumoral perfusion and proton spectroscopic MR imaging.

ASSESSMENT OF BRAIN METASTASES VOLUME CONTROL DURING STEREOTACTIC RADIOSURGERY BY LONGITUDINAL REGION GROWTH MR IMAGE SEGMENTATION ANALYSIS