0000000000709366

AUTHOR

M. Nieminen

Progression From Paroxysmal to Persistent Atrial Fibrillation. Clinical Correlates and Prognosis

Objectives: We investigated clinical correlates of atrial fibrillation (AF) progression and evaluated the prognosis of patients demonstrating AF progression in a large population. Background: Progression of paroxysmal AF to more sustained forms is frequently seen. However, not all patients will progress to persistent AF. Methods: We included 1,219 patients with paroxysmal AF who participated in the Euro Heart Survey on AF and had a known rhythm status at follow-up. Patients who experienced AF progression after 1 year of follow-up were identified. Results: Progression of AF occurred in 178 (15%) patients. Multivariate analysis showed that heart failure, age, previous transient ischemic attac…

research product

Survival and growth of transplantedFontinalis dalecarlica (Bryophyta) in controlled flow and short-term regulated flow sites in the Perhonjoki River, Western Finland

Impoundment, channelisation and short-term regulation of the Perhonjoki river have caused changes in the distribution and abundance of aquatic mosses. While some moss species have colonised the beds in the channelised and short-term regulated part of the river, Fontinalis spp. are mainly restricted to the sites above the power plant where flow variability is low. Therefore, as a first step towards gaining a better understanding of the factors contributing to the distribution and abundance of Fontinalis dalecarlica (Bruch & Schimp, Fontinalaceae) in the Perhonjoki, a transplant experiment was conducted to test whether short-term flow regulation restricts the survival and growth of this speci…

research product

Sex differences in renal damage induced in the mouse by Amanita virosa.

Summary The sensitivity of male and female mice to Amanita virosa was compared. Dried, homogenizedmushroom was given orally by stomach tubing at doses of 100, 200, 400 and 800 mg dried mushroom/kg body weight. Both in males and in females, the kidneys were the only organs showing macroscopical changes. The dose of 100 mg/kg caused renal damage in females, whereas in males the first signs of kidney damage were seen at the dose of 400 mg/kg. The renal lesions observed in the males were located in the cortex, while in the females they were limited to the outer stripe of the outer medullary zone. Testectomy diminished the nephrotoxicity of A. virosa in male mice and caused changes in the locali…

research product