0000000000711294

AUTHOR

Christoph Schmidt

0000-0002-2309-3209

showing 2 related works from this author

Quartz OSL dating of late quaternary Chinese and Serbian loess: A cross Eurasian comparison of dust mass accumulation rates

2019

© 2018 Elsevier Ltd and INQUA. Reconstructing dust Mass Accumulation Rate (MAR) from loess deposits is critical to understanding past atmospheric mineral dust activity and requires accurate independent age models from loess deposits across Europe and Asia. Previous correlations of loess in Europe and China have tended to focus on multi-millennial timescales, with no detailed examination of dust MAR at the two ends of the Eurasian loess belt on shorter, sub-orbital scales. Here we present a detailed quartz optically stimulated luminescence (OSL) chronology from the Serbian Titel Loess Plateau (Veliki Surduk loess core) and the Chinese Loess Plateau (Lingtai section). The luminescence ages pa…

010506 paleontologyTitel loess plateau010504 meteorology & atmospheric sciencesOptically stimulated luminescenceOSL datingGeochemistryLoessDustMars Exploration ProgramMineral dust01 natural sciencesMARLoessChinese Loess PlateauGlacial periodQuaternary[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]QuartzGeologyComputingMilieux_MISCELLANEOUS0105 earth and related environmental sciencesEarth-Surface ProcessesChronology
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Hyaluronic Acid Increases Anti-Inflammatory Efficacy of Rectal 5-Amino Salicylic Acid Administration in a Murine Colitis Model

2021

5-amino salicylic acid (5-ASA) is a standard therapy for the treatment of mild to moderate forms of inflammatory bowel diseases (IBD) whereas more severe forms involve the use of steroids and immunosuppressive drugs. Hyaluronic acid (HA) is a naturally occurring non-sulfated glycosaminoglycan that has shown epithelium protective effects in experimental colitis recently. In this study, both 5-ASA (30 mg/kg) and HA (15 mg/kg or 30 mg/kg) were administered rectally and investigated for their potential complementary therapeutic effects in moderate or severe murine colitis models. Intrarectal treatment of moderate and severe colitis with 5-ASA alone or HA alone at a dose of 30 mg/kg led to a sig…

Drug5-amino salicylic acidmedicine.drug_classHyaluronic acidmedia_common.quotation_subjectInflammationPharmacologyBiochemistryInflammatory bowel diseaseInflammatory bowel diseaseAnti-inflammatorychemistry.chemical_compoundDrug DiscoveryHyaluronic acidmedicineColitismedia_commonInflammationPharmacologybusiness.industryTherapeutic effectColitismedicine.diseasechemistryMolecular MedicineOriginal Articlemedicine.symptombusinessSalicylic acidBiomolecules & Therapeutics
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