0000000000711764

AUTHOR

Robyn E Wootton

showing 2 related works from this author

The effects of age at menarche and first sexual intercourse on reproductive and behavioural outcomes:A Mendelian randomization study

2020

SummaryThere is substantial variation in the timing of significant reproductive life events such as menarche and first sexual intercourse. Life history theory explains this variation as an adaptive response to the developmental environment. In environments characterized by harsh conditions, adopting a fast life history strategy may increase fitness. In line with this, there is evidence demonstrating that greater childhood adversity is associated with earlier age at menarche. Here we applied Mendelian randomization (MR) methods to investigate whether there is a causal effect of variation in age at menarche and age at first sexual intercourse on outcomes related to reproduction, education and…

MalePhysiologySocial SciencesFamilies0302 clinical medicineEndocrinologyMathematical and Statistical TechniquesSociologyReproductive PhysiologyPregnancyCopulationMedicine and Health SciencesPsychology030212 general & internal medicineChildrenLife History Traitsmedia_common0303 health sciencesMultidisciplinaryAlcohol ConsumptionReproductionStatisticsQAge FactorsCoitusRGenomicsMetaanalysisMiddle AgedCausalityPhysical SciencesMenarcheEducational StatusMedicineFemaleReproductionPsychologyResearch Articlemedia_common.quotation_subjectScienceAffect (psychology)Research and Analysis MethodsLife history theoryEducation03 medical and health sciencesRisk-TakingMendelian randomizationmedicineGenome-Wide Association StudiesGeneticsHumansSocial determinants of healthStatistical MethodsMenstrual CycleEducational Attainment030304 developmental biologyNutritionMenarchePregnancyBehaviorEndocrine PhysiologyBiology and Life SciencesComputational BiologyHuman GeneticsMendelian Randomization Analysismedicine.diseaseGenome AnalysisConfidence intervalEducational attainmentUnited KingdomDietSexual intercourseAge GroupsPeople and PlacesPopulation GroupingsMathematicsDemography
researchProduct

A meta-review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders

2020

There is increasing academic and clinical interest in how "lifestyle factors" traditionally associated with physical health may also relate to mental health and psychological well-being. In response, international and national health bodies are producing guidelines to address health behaviors in the prevention and treatment of mental illness. However, the current evidence for the causal role of lifestyle factors in the onset and prognosis of mental disorders is unclear. We performed a systematic meta-review of the top-tier evidence examining how physical activity, sleep, dietary patterns and tobacco smoking impact on the risk and treatment outcomes across a range of mental disorders. Result…

medicine.medical_specialtyPsychological interventiondietary patternsphysical activityLifestyle factorslaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialanxiety disorderslawmedicineANXIETYBipolar disordertobacco smokingsleepLifestyle factors mental disorders psychological well-being physical activity sedentary behavior tobacco smoking dietary patterns sleep depression anxiety disorders bipolar disorder schizophreniaPsychiatryMETAANALYSISPsychiatrybipolar disorderRISKScience & Technologybusiness.industryPublic healthSEDENTARY BEHAVIORResearch ReportsASSOCIATIONADULTSMental illnessmedicine.diseaseMental healthHEALTH PROBLEMS030227 psychiatrymental disordersschizophreniaPsychiatry and Mental healthPHYSICAL-ACTIVITYSchizophreniaDEPRESSIVE SYMPTOMSdepressionMENDELIAN RANDOMIZATIONAnxietypsychological well-beingPshychiatric Mental Healthmedicine.symptombusinessLife Sciences & Biomedicine030217 neurology & neurosurgery
researchProduct