0000000000714407

AUTHOR

Maria Paola Germanò

showing 3 related works from this author

Chemical characterization of Anthemis parlatoreana fresh and dried aerial parts by GC and LC chromatographic techniques and evaluation of the antioxi…

2022

Anthemis parlatoreana was collected in the north west coast of Sicily. Fresh and dried aerial parts were subjected to distillation procedure for the extraction and isolation of essential oils. In both fresh and dried samples, the most abundant chemical classes were ketones and esters, represented to a greater extent by β-thujone and β-artemisia acetate, respectively. In dried vegetable material, a high content of α-pinene and δ3-carene was also registered. Aqueous, methanol and ethyl acetate extracts of aerial parts were also investigated in terms of polyphenolic content and antioxidant potential. All the extracts tested showed a quite different quali-quantitative profile and in terms of ch…

essential oil distillationGC-MS/FIDAnthemis parlatoreanaSettore BIO/02 - Botanica SistematicaHPLC-PDA/MSPlant ScienceSettore BIO/15 - Biologia FarmaceuticaEcology Evolution Behavior and Systematicspolyphenolsterpenes
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Polyphenol Characterization, Antioxidant and Skin Whitening Properties of Alnus cordata Stem Bark

2019

In this study, we investigated the phenolic composition of the crude extract (MeOH 80 %) of Alnus cordata (Loisel.) Duby stem bark (ACE) and its antioxidant and skin whitening properties. RP-LC-DAD analysis showed a high content of hydroxycinnamic acids (47.64 %), flavanones (26.74 %) and diarylheptanoids (17.69 %). Furthermore, ACE exhibited a dose-dependent antioxidant and free-radical scavenging activity, expressed as half-maximal inhibitory concentration (IC50 ): Oxygen radical absorbance capacity (ORAC, IC50 1.78 μg mL-1 )>Trolox equivalent antioxidant capacity (TEAC, IC50 3.47 μg mL-1 )>2,2-Diphenyl-1-picrylhydrazyl (DPPH, IC50 5.83 μg mL-1 )>β-carotene bleaching (IC50 11.58 μg mL-1 )…

AntioxidantOxygen radical absorbance capacityDPPHmedicine.medical_treatmentTrolox equivalent antioxidant capacityBioengineeringAlnus cordata; antimelanogenic activity; Betulaceae; mushroom tyrosinase; polyphenols; RP-LC-DAD analysis; zebrafish; Alnus; Animals; Antioxidants; Biphenyl Compounds; Enzyme Inhibitors; Monophenol Monooxygenase; Picrates; Plant Bark; Plant Extracts; Polyphenols; Skin; ZebrafishAlnus01 natural sciencesBiochemistryAntioxidantschemistry.chemical_compoundPicratesmedicineAnimalsFood scienceEnzyme InhibitorsMolecular BiologyIC50ZebrafishSkinbiologyMonophenol MonooxygenasePlant Extracts010405 organic chemistryBiphenyl CompoundsPolyphenolsSkin whiteningGeneral ChemistryGeneral Medicinebiology.organism_classificationAlnus cordata0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryPolyphenolPlant BarkMolecular Medicine
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Alnus glutinosa (L.) Gaertn. and Alnus cordata (Loisel) Duby as new sources of safe cosmetic and pharmacological anti-melanogenic agents

2018

The genus Alnus (Betulaceae) comprises many species with a long history in traditional medicines. The crude extracts and isolated compounds from Alnus species exhibit a wide spectrum of in vitro and in vivo pharmacological activities (1). Phytochemical investigations revealed the presence of diarylheptanoids, a class of natural products typically found in Alnus genus with two aryl groups joined by a heptane chain in the main skeleton that have drawn attention due to their multiple biological properties and their therapeutic potential (2). A previous study reported that oregonin and other structurally analogous diarylheptanoids isolated from the bark of A. hirsuta showed inhibitory effects o…

Settore BIO/15 - Biologia FarmaceuticaBetulaceae traditional medicinespharmacological activities endemic species skin disorders
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