0000000000715483

AUTHOR

Francesco Cappuccio

Three-Dimensional Separation and Characterization of Fractures in X-Ray Computed Tomographic Images of Rocks

Open fractures can affect petrophysical properties of their host rock masses, as well as fluid transport and storage, so characterization of them is important to both industrial and research scientists. X-ray Computed Tomography (CT), a non-destructive technique for 3D imaging of various materials, shows such fractures well in rock samples. However, separation and characterization of fractures in CT data is complicated when a scanned sample contains narrow and intersecting fractures, because narrow fractures become blurred when thinner than the scanner resolution and their value approximates the one of the matrix, and because intersecting features are difficult to individually characterize.…

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The estimation of porosity in Japan Trench plate boundary using low-resolution X-ray computed tomography (XCT) images and laboratory measurements

Abstract. X-ray computed tomography (XCT) is an advanced imaging technique that has been increasingly used in the past years because it can provide valuable information on internal structures of a rock sample in a non-invasive manner. The maximum resolution of lab-based XCT facilities is ~0.5 μm, which might be sufficient to capture macropores in some rocks (i.e., sandstone), but will result in underestimation of porosity in clay-rich sediments containing micro-and nano-scale pores. Furthermore, such high-resolution XCT facilities are quite expensive and not ubiquitous. In this study, we introduce a new methodology based on the K-means clustering algorithm to process of low-resolution XCT i…

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Hematologic toxicity of radium-223 in elderly patients with metastatic Castration Resistant Prostate Cancer: a real-life experience

Background: Treatment with radium-223 has been shown to increase survival and to delay skeletal events related to bone metastases of patients with metastatic Castration Resistant Prostate Cancer (mCRPC). This treatment has also proved to be well tolerated, and hematological toxicity, in particular anemia, represents the most represented adverse event. Materials and methods: We evaluated the hematologic toxicity of Ra-223 treatment in a real-life experience of 38 patients from two Italian cancer centers, with bone metastases from mCRPC. The main endpoint of the study was the evaluation of the efficacy and tolerability of treatment with radium-223, with greater reference to hematological toxi…

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