0000000000717474

AUTHOR

Minafra L

showing 3 related works from this author

The Pvt-1 oncogene is a target of Myc and its expression is deregulated in neuroblastoma cells

2003

NeuroblastomaPvt-1MycOncogene
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Inflammatory Response to a High Radiation Dose in Breast Cancer

2014

Background: Radiation therapy (RT) is an essential treatment modality used for breast cancer (BC) care. Radiations can stimulate the immune system via the early activation of cytokine cascades, which can greatly affect cellular radio-sensitivity. Our aim is to analyze inflammatory response induced by high ionizing radiation (IR) doses, generated by intraoperative radiotherapy (IORT) treatment, to identify several potential targets that may influence cell radio-response. Methods: MCF10, MCF7 and MDA-MB231 BC cell lines have been exposed to high IR (23 Gray and 9 Gray), delivered by IORT treatments. Conditioned media (CM) were assayed at the time points: 0’, 30’, 1, 3, 6, 24, 48, and 72 hours…

Settore MED/05 - Patologia ClinicaBreast cancer IORT cytokine production
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A type I interferon (IFN)-induced distal enhancer differentially regulates the P1 and P2 c-Myc promoters

2005

c-MycIFN
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