0000000000717640
AUTHOR
Syrina Al Aïn
Orientation of newborn mice to lactating females: Identifying biological substrates of semiochemical interest
International audience; Among mammals, odor-based communication between females and infants is decisive for neonatal survival. So far, the nature of odor substrates involved in the localization of the mother and their nipples is unknown in mice. The present study aims: (1) to evaluate the specific attractive value of lactating females to newborn mice, (2) to localize the abdominal region that is most attractive to pups, and (3) to identify odor substrates that support such attraction. Results showed that 5-6-day-old mice roam preferentially over the abdomen of lactating females than the abdomen of non-lactating females. In lactating females, pups are more attracted to abdominal areas compri…
Testing Smell When It Is Really Vital: Behavioral Assays of Social Odors in the Neonatal Mouse
The initial interactions of mouse newborns with their mother are crucial for their survival. These interactions rapidly end in the pups reaching nipples and getting milk. While we realize that olfaction is clearly prevailing in the success of these first suckling episodes, we still understand little about the nature and range of the natural odorants involved. Here we non-exhaustively describe some experimental principles and methods to assay the behavior of newly born and infant mice exposed to different odor stimuli from conspecifics. Testing neonatal and young mice with chemostimuli which they are evolutionarily or developmentally canalized to detect may be a productive way to trace unant…
Suckling odours in rats and mice: biological substrates that guide newborns to the nipple
Proceedings Paper 12th Meeting of the Chemical Signals in Vertebrates, Aug 28-31, 2011, Berlin, GERMANY ; http://www.springer.com/life+sciences/ecology/book/978-1-4614-5926-2; International audience; It is a general strategy for mammalian females to emit odour signals to direct their offspring to the mammae and to motivate their suckling. The survival of newborns depends on their own capacities to exploit the cues emitted by their mother, or by conspecific lactating females, and to direct their behaviour to the vital targets on the mother's body-the nipples. This chapter synthesises data on some natural substrates that contribute to nipple searching and grasping in the newborns of (laborato…
An exploration of mammary odor cues in newborn mice
International audience
Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alteration
Early exposure to odorants pre-, post- or transnatally is known to. result in a decreased avoidance or increased preference for these. odorants in mammals. There are also indications that olfactory sensitivity. for these odorants can be affected. We exposed C57-Bl/6. mice of Mor23-GFP and M71-GFP lines to lyral (LY) or acetophenone. (AC), respectively, either transnatally through the water of the. mother (1*10-5 M) or postnatally in air for 1 hr per day (20 ll pure). Animals were weaned on postnatal day 20 (P20), and 3 tests were. performed:. 1) A 3-min exploration test on P20 in a rectangular arena presenting. LY and AC under a wire mesh to measure the time spent in each. half of the arena…
How does a newly born mouse get to the nipple? odor substrates eliciting first nipple grasping and sucking responses
It is a mammalian female strategy to emit odor cues and signals that direct their inexperienced newborns to the nipple, and optimize their initial sucking success and, hence, viability. Here, natural odorous substrates that contribute to nipple grasping were investigated in mice, a species that has not been much scrutinized on this topic. The response of pups toward the nipples of lactating females (LF) versus nonlactating females (NLF) were first assessed right after watched birth, before and after the first suckling experience, and at 1 day old, after more extended suckling experience. It appeared that only nipples of LF induced grasping at these early ages, leading to take NLF as the bas…
Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alterations
National audience
Selectivity of C57BL/6 and BALB/c newborn mice to the odors of milk and nipple differing in lactational age and strain
Selectivity of C57BL/6 and BALB/c newborn mice to the odors of milk and nipple differing in lactational age and strain. 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO)
An odor timer in milk? Synchrony in the odor of milk effluvium and neonatal chemosensation in the mouse.
International audience; Mammalian newborns exhibit avid responsiveness to odor compounds emanating from conspecific milk. Milk is however developmentally heterogeneous in composition as a function of both evolved constraints and offspring demand. The present study aimed to verify whether milk odor attractivity for neonates is equally distributed along lactation in Mus musculus (Balb-c strain). Therefore, we exposed pups varying in age to milk samples collected from females in different lactational stages. The pups were assayed at postnatal days 2 (P2), 6 (P6) and 15 (P15) in a series of paired-choice tests opposing either murine milk and a blank (water), or two samples of milk collected in …