Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium

Purpose : To investigate the association of common systemic medication use with intraocular pressure and glaucoma prevalence in the European population.Methods : We examined associations of systemic medication use with intraocular pressure and glaucoma prevalence in a meta-analysis of multiple cohort studies of the European Eye Epidemiology (E3) consortium. IOP measurement method and glaucoma ascertainment were according to individual study protocols. Multivariable regression (linear for IOP and logistic for glaucoma prevalence) was carried out in each study and results pooled using random effects meta-analysis. Age, sex, body-mass index and diabetes were included as co-variables. Associati…

Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration in Europeans: A meta-analysis of the European Eye Epidemiology (E3) - consortium

Purpose : Changes in lipid metabolism, chronic inflammation and increased oxidative stress have been discussed as patho-etiogenetic drivers in age-related macular degeneration (AMD). Systemic medication, such as lipid-lowering drugs (LLD) and anti-diabetic drugs, affect these pathways and may therefore also play a role in AMD pathogenesis. We aimed to investigate associations of commonly used systemic drugs with AMD prevalence in the European population.Methods : We included 38,694 adults from 14 population-based studies from the European Eye Epidemiology (E3) consortium. We performed multivariable logistic regression modelling to examine medication use association with prevalence of AMD as…

A Pharmacoepidemiological study of intravitreal drug consumption in the first 12 months of treatment. The EPIdemiology and SAFEty collaboration

Trends in eye care use in adults treated for diabetes between 2008 and 2017 in France: a nationwide study

PRÉDICTION DU CONTENU DE LA RÉTINE EN ACIDES GRAS POLYINSATURÉS OMÉGA-3 À TRAVERS LE DOSAGE DE 7 MOLÉCULES D'ESTERS DE CHOLESTÉROL

La présente invention concerne une méthode de détermination du contenu en acides gras polyinsaturés oméga-3 de la rétine d’un sujet comprenant la détermination de la teneur en au moins un ester de cholestérol dans un échantillon sanguin dudit sujet, le contenu en acides gras polyinsaturés oméga-3 de la rétine étant corrélé à la teneur dudit au moins un ester de cholestérol, ledit au moins un ester de cholestérol étant le cholesteryl 5,8,11,14,17-eicosapentaenoate.