0000000000729025
AUTHOR
S. Brunner
High Resolution Mass Spectrometry of Light Ions in a Penning Trap
AB1358 Infectious antibodies repertoire in rheumatoid arthritis
Background The incidence of infectious diseases in the RA ADAPTHERA study by ELISA antibody screening and the differences in infectious distribution in active or low active disease patients was explored. Methods Sera from 88 naive RA patients out of the ADAPTHERA study cohort, disease duration Results 82% RA patients were found to be positive for HSV1 +2 IgG (2% IgM positive), 8% for Adenovirus (IgA), 77% (IgG), and 1% (IgM). 99% for EBV-IgG (no IgM positive). 53% (IgG), and 26% (IgM) for CMV. 38% for HP-IgG and 15% for IgA and 79% for P-B19-IgG (3% IgM). 6% for Borrelia-IgM and 14% for IgG. A slightly increase was found for EBV sera positivity (99% IgG), compared to the normal population. …
Determination of the helium-4 mass in a Penning trap
We have measured the cyclotron frequencies of He+, H+ 2 and D+ 2 ions in a room temperature Penning trap. The resonances were detected destructively by a time-of-flight technique. The statistical uncertainty of the resonance frequencies was generally below 1 ppb. A detailed account of measures to minimize systematic frequency shift is presented. Using the accepted values for the proton and deuteron mass we obtain a value for the 4He mass: M(4 He) = 4.0026032489(22) (0.5 ppb). It is in agreement with the accepted value.