0000000000730522

AUTHOR

Luigi Piva

showing 2 related works from this author

Treatment of high-risk relapsed Wilms tumor with dose-intensive chemotherapy, marrow-ablative chemotherapy, and autologous hematopoietic stem cell su…

2008

Background We evaluated an intensified chemotherapy strategy in children with Wilms tumor who relapsed with high-risk features. Procedures From January 2001 to June 2006, we treated 20 consecutive children with reinduction chemotherapy (using ifosfamide/carboplatin/etoposide in 15/20 cases), with (n = 15) or without (n = 5) subsequent high-dose chemotherapy and hematopoietic stem cell support, surgery where feasible, and radiation therapy. The median time to relapse was 10 months after nephrectomy. All but two children initially received doxorubicin as first-line therapy. Results All patients were assessed for outcome: 13 are currently alive, 12 of them in remission a median 25 months since…

OncologyMaleTransplantation Conditioningmedicine.medical_treatmentHematopoietic stem cell transplantationNephrectomyPediatricschemistry.chemical_compoundHigh-dose chemotherapyRelapseChildIfosfamideGraft SurvivalRemission InductionHematopoietic Stem Cell TransplantationHematologyPerinatology and Child HealthSurvival RateTreatment OutcomeItalyOncologyChild PreschoolAbsolute neutrophil countFemaleAutologousmedicine.drugmedicine.medical_specialtyAntineoplastic AgentsTransplantation AutologousWilms TumorInternal medicinemedicineHumansPreschoolSurvival rateSalvage TherapyChemotherapyTransplantationbusiness.industryInfantWilms' tumormedicine.diseaseCarboplatinSurgeryRadiation therapychemistryPediatrics Perinatology and Child HealthAutologous hematopoietic stem cell transplantation; High-dose chemotherapy; Relapse; Wilms tumor; Antineoplastic Agents; Child; Child Preschool; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Infant; Italy; Male; Nephrectomy; Remission Induction; Salvage Therapy; Survival Rate; Transplantation Conditioning; Transplantation Autologous; Treatment Outcome; Wilms Tumor; Pediatrics Perinatology and Child Health; Hematology; OncologybusinessAutologous hematopoietic stem cell transplantation
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Teratoma with a malignant somatic component in pediatric patients: The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience

2010

Background Teratoma with a malignant somatic component (TMSC) is rare but described in adults, whereas information on pediatric presentation is sparse. Procedure The Associazione Italiana Ematologia Oncologia Pediatrica identified 14 cases of TMSC. Clinical files and pathology specimens were reviewed. Results The series (9 female, 5 male) showed the following disease: testis (2), sacrococcygeal (3), ovary (3), retroperitoneum (3), mediastinum (2), and foot soft tissue (1). Distribution of the somatic component was: carcinoma (4), pancreatic neuroendocrine tumor (1), neuroblastoma (3), rhabdomyosarcoma (3), rhabdomyosarcoma plus liposarcoma, chondrosarcoma, neurogenic sarcoma (1), chondrosar…

medicine.medical_specialtyPathologybusiness.industryMalignant peripheral nerve sheath tumorHematologyLiposarcomamedicine.diseaseOncologyPediatrics Perinatology and Child HealthmedicineCarcinomaRadiologyGerm cell tumorsTeratomaSarcomaChondrosarcomaRhabdomyosarcomabusinessPediatric Blood & Cancer
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