0000000000731337

AUTHOR

Aleksandra Stefanović

showing 2 related works from this author

Effects of Gestational Diabetes Mellitus on Cholesterol Metabolism in Women with High-Risk Pregnancies: Possible Implications for Neonatal Outcome

2022

Metabolic disorders in pregnancy, particularly gestational diabetes mellitus (GDM), are associated with an increased risk for adverse pregnancy outcome and long-term cardiometabolic health of mother and child. This study analyzed changes of serum cholesterol synthesis and absorption markers during the course of high-risk pregnancies, with respect to the development of GDM. Possible associations of maternal lipid biomarkers with neonatal characteristics were also investigated. The study included 63 women with high risk for development of pregnancy complications. Size and proportions of small low-density (LDL) and high-density lipoprotein (HDL) particles were assessed across trimesters (T1&nd…

cholesterol synthesis and absorptionEndocrinology Diabetes and Metabolismhigh-risk pregnancy; gestational diabetes; cholesterol synthesis and absorption; LDL and HDL particles; neonatal outcomeLDL and HDL particles cholesterol synthesis and absorption gestational diabetes high-risk pregnancy neonatal outcomehigh-risk pregnancygestational diabetesLDL and HDL particlesMolecular BiologyBiochemistryneonatal outcome
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Diabetes and Colorectal Cancer Risk: A New Look at Molecular Mechanisms and Potential Role of Novel Antidiabetic Agents.

2021

Epidemiological data have demonstrated a significant association between the presence of type 2 diabetes mellitus (T2DM) and the development of colorectal cancer (CRC). Chronic hyperglycemia, insulin resistance, oxidative stress, and inflammation, the processes inherent to T2DM, also play active roles in the onset and progression of CRC. Recently, small dense low-density lipoprotein (LDL) particles, a typical characteristic of diabetic dyslipidemia, emerged as another possible underlying link between T2DM and CRC. Growing evidence suggests that antidiabetic medications may have beneficial effects in CRC prevention. According to findings from a limited number of preclinical and clinical stud…

Oncologyendocrine system diseasesColorectal cancerComorbidityReview0302 clinical medicineinsulin resistanceEpidemiologyBiology (General)small dense LDLSpectroscopyglucagon-like peptide-1 receptor agonists0303 health sciencesIncidenceGeneral MedicineSmall dense LDL3. Good healthComputer Science ApplicationsLipoproteins LDLChemistry030220 oncology & carcinogenesismedicine.symptomColorectal Neoplasmsmedicine.medical_specialtyQH301-705.5InflammationCatalysisGlucagon-like peptide-1 receptor agonistsGlucagon-Like Peptide-1 ReceptorInorganic Chemistry03 medical and health sciencesInsulin resistanceInternal medicineDiabetes mellitusmedicineHumansHypoglycemic AgentsIn patientPhysical and Theoretical ChemistryQD1-999Molecular BiologyAntidiabetic agents030304 developmental biologyInflammationbusiness.industryOrganic ChemistryType 2 Diabetes Mellitusnutritional and metabolic diseasesInsulin resistanceGlucagon-like peptide-1 receptor agonists Hyperglycemia Inflammation Insulin resistance Comorbidity Diabetes Mellitus Type 2 Glucagon-Like Peptide-1 Receptor Humans Hyperglycemia Hypoglycemic Agents Incidence Lipoproteins LDL Oxidative Stress Colorectal Neoplasms Small dense LDLmedicine.diseasedigestive system diseasesOxidative StressDiabetes Mellitus Type 2Oxidative stressinflammationHyperglycemiabusinessInternational journal of molecular sciences
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