0000000000735457

AUTHOR

Francesca Caputo

showing 3 related works from this author

Moving Immune Checkpoint Inhibitors to Early Non-Small Cell Lung Cancer: A Narrative Review

2022

Simple Summary Moving from the achievements of immune checkpoint inhibitors in metastatic lung cancer, the great promise of immunotherapy in resectable early-stage is to make a disease, often lethal until now for frequent post-surgery relapses, more curable. This review focuses on role of immunotherapy in early-stage non-small cell lung cancer. We summarize biological rationale, findings from clinical trials of adjuvant and neoadjuvant immune checkpoint inhibitors, questions about biomarkers and choice of endpoints, aiming to provide up-to-date information useful for clinical decision making. Lung cancer is the leading cause of cancer-related death worldwide. Since prognosis of early-stage …

immune checkpoint inhibitorsCancer Researchlung cancernon-small-cell lung carcinoma (NSCLC)OncologyadjuvantSettore MED/06 - Oncologia Medicaneoadjuvantadjuvant; immune checkpoint inhibitors; immunotherapy; lung cancer; neoadjuvant; non-small-cell lung carcinoma (NSCLC);immune checkpoint inhibitorimmunotherapy
researchProduct

Adherence and Reactogenicity to Vaccines against SARS-COV-2 in 285 Patients with Neuropathy: A Multicentric Study

2022

Background: The safety of the new vaccines against SARS-CoV-2 have already been shown, although data on patients with polyneuropathy are still lacking. The aim of this study is to evaluate the adherence to SARS-CoV-2 vaccination, as well as the reactogenicity to those vaccines in patients affected by neuropathy. Methods: A multicentric and web-based cross-sectional survey was conducted among patients affected by neuropathy from part of South Italy. Results: Out of 285 responders, n = 268 were included in the final analysis and n = 258 of them (96.3%) were fully vaccinated. Adherence to vaccination was higher in patients with hereditary neuropathies compared to others, while it was lower in …

General NeuroscienceSARS-CoV-2 infectionCIDP COVID-19 vaccines SARS-CoV-2 infection autoimmune neuropathy hereditary neuropathy neuropathy reactogenicity vaccine hesitancy vaccine safetyreactogenicityvaccine hesitancySARS-CoV-2 infection; COVID-19 vaccines; reactogenicity; vaccine safety; vaccine hesitancy; neuropathy; autoimmune neuropathy; hereditary neuropathy; CIDPneuropathyvaccine safetyCIDPhereditary neuropathyCOVID-19 vaccineautoimmune neuropathy
researchProduct

Effectiveness of a Psychosocial Care Quality Improvement Strategy to Address Quality of Life in Patients with Cancer: The HuCare2 Stepped-Wedge Clust…

2021

Key Points Question Does an implementation strategy integrating psychosocial care into cancer centers improve at least 1 of 2 domains (emotional or social function) of health-related quality of life? Findings This stepped-wedge cluster randomized clinical trial included 762 patients with cancer at high risk for reduced quality of life. Health-related quality of life score improved from baseline to 3 months among participants in the Humanization in Cancer Care Quality Improvement Strategy arm vs the usual care arm, showing a statistically significant difference for emotional function, but not for social function. Meaning This study suggests the use of an implementation strategy aiming to pro…

Malemedicine.medical_specialtyQuality managementPsychological interventionPsychiatric Rehabilitationlaw.inventionQuality of life (healthcare)Randomized controlled triallawNeoplasmsMedicineCluster AnalysisHumansCluster randomised controlled trialOriginal InvestigationAgedbusiness.industryResearchCancer Care FacilitiesGeneral MedicineOdds ratioMiddle AgedQuality ImprovementAged; Cluster Analysis; Cross-Sectional Studies; Female; Humans; Italy; Male; Middle Aged; Neoplasms; Psychiatric Rehabilitation; Quality of Life; Quality ImprovementOnline OnlyCross-Sectional StudiesOncologyItalyPhysical therapyQuality of LifeFemalebusinessPsychosocial
researchProduct