Author: Suvi Holmstedt

0000000000735683

AUTHOR

Suvi Holmstedt

Deoxygenative Divergent Synthesis : En Route to Quinic Acid Chirons

The installation of vicinal mesylate and silyl ether groups in a quinic acid derivative generates a system prone for stereoselective borane-catalyzed hydrosilylation through a siloxonium intermediate. The diversification of the reaction conditions allowed the construction of different defunctionalized fragments foreseen as useful synthetic fragments. The selectivity of the hydrosilylation was rationalized on the basis of deuteration experiments and computational studies. peerReviewed

research product

CCDC 2005907: Experimental Crystal Structure Determination

Related Article: Suvi Holmstedt, Lijo George, Alisa Koivuporras, Arto Valkonen, Nuno R. Candeias|2020|Org.Lett.|22|8370|doi:10.1021/acs.orglett.0c02995

research product

PEPhysical Sciences and Engineering
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LSLife Sciences
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SHSocial Sciences and Humanities
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