0000000000736116

AUTHOR

Mauro Moroni

showing 3 related works from this author

Clinical Epidemiological Survey of Legionella pneumophila Infections in Italy

1986

A clinical epidemiological survey of Legionella pneumophila infections occurring in Italy between 1 December 1985 and 31 May 1986 was carried out to evaluate the incidence of sporadic, epidemic and nosocomial L. pneumophila pneumonia. A total of 355 cases of pneumonia were studied of which 11.5% were due to Gram positive bacteria, 11% were due to Gram negative bacteria, 7.9% were due to Mycoplasma pneumoniae, 4.5% were due to L. pneumophila and 8.5% were due to sundry aetiological agents. The remainder (45.6%) could not be diagnosed accurately. In addition, the anti L. pneumophila antibody titres were assessed. The results are discussed in terms of the occurrence of the disease in Italy an…

AdultMalemedicine.medical_specialtyMycoplasma pneumoniaeGram-negative bacteriaAdolescentGram-positive bacteriamedicine.disease_causeBiochemistryLegionella pneumophilaMicrobiologyEpidemiologymedicineHumansChildAgedAged 80 and overbiologybusiness.industryIncidence (epidemiology)Biochemistry (medical)InfantCell BiologyGeneral MedicineMiddle Agedmedicine.diseasebiology.organism_classificationrespiratory tract diseasesPneumoniaItalyChild PreschoolEtiologyFemaleLegionnaires' DiseasebusinessJournal of International Medical Research
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Problems in the management of chronic hepatitis B with interferon: experience in a randomized, multicentre study.

1990

In a multicentre trial, 82 patients known to be hepatitis B e antigen and hepatitis B virus DNA positive for at least 1 year, with elevated serum alanine aminotransferase levels and chronic liver lesions on biopsy, were randomized to receive either recombinant interferon alfa-2a at a dose of 4.5 million units thrice weekly for 4 months or no treatment. At the end of therapy, viral DNA clearance and aminotransferase normalization were significantly (p less than 0.05) more frequent in treated patients than in controls. After 16 months' follow up, the difference was still significant for hepatitis B e antigen clearance and transaminase normalization. Hepatitis B virus DNA reactivation was obse…

AdultMaleAlpha interferonInterferon alpha-2medicine.disease_causeTransaminaseLiver diseaseInterferonBiopsymedicineHumanschronic hepatitis BHepatitis B e AntigensHepatitis B virustherapyHepatitis B Surface AntigensHepatologybiologymedicine.diagnostic_testbusiness.industryInterferon-alphaAlanine TransaminaseinterferonHepatitis Bmedicine.diseaseHepatitis BRecombinant ProteinsAlanine transaminaseLiverImmunologyChronic Diseasebiology.proteinFemalechronic hepatitis B; therapy; interferonbusinessBiomarkersmedicine.drugFollow-Up StudiesJournal of hepatology
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Role of PCR in Diagnosis and Prognosis of Visceral Leishmaniasis in Patients Coinfected with Human Immunodeficiency Virus Type 1

2001

ABSTRACT A group of 76 consecutive human immunodeficiency virus (HIV)-positive patients with fever of unknown origin ( n = 52) or fever associated with pulmonary diseases was evaluated in order to assess the usefulness of PCR with peripheral blood in the diagnosis and follow-up of visceral leishmaniasis. We identified 10 cases of visceral leishmaniasis among the 52 patients with fever of unknown origin. At the time of diagnosis, all were parasitemic by PCR with peripheral blood. During follow-up, a progressive decline in parasitemia was observed under therapy, and all patients became PCR negative after a median of 5 weeks (range, 6 to 21 weeks). However, in eight of nine patients monitored …

AdultMaleMicrobiology (medical)Settore MED/17 - Malattie InfettiveLeishmania donovaniHIV InfectionsParasitemiaPolymerase Chain ReactionImmunopathologymedicineAnimalsHumansLeishmania infantumFever of unknown originbiologyLeishmaniasisDNA ProtozoanMiddle AgedPrognosisvisceral leishmaniasis; HIV; PCR diagnosisSettore MED/07 - Microbiologia e Microbiologia Clinicabiology.organism_classificationmedicine.diseaseVisceral leishmaniasisImmunologyHIV-1Leishmaniasis VisceralFemaleParasitologyViral diseaseLeishmania infantumPolymorphism Restriction Fragment LengthLeishmania donovaniJournal of Clinical Microbiology
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