0000000000740293

AUTHOR

Ea Khan

showing 6 related works from this author

Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

2022

Abstract Background Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). Precise HIV burden information is critical for effective geographic and epidemiological targeting of prevention and treatment interventions. Age- and sex-specific HIV prevalence estimates are widely available at the national level, and region-wide local estimates were recently published for adults overall. We…

MaleAdultSettore MED/17 - Malattie InfettiveAdolescentSettore MED/42 - Igiene Generale e ApplicataHIV InfectionsSettore MED/01 - Statistica MedicaYoung AdultHIV Infections/prevention & controlPregnancySeroepidemiologic StudiesGeneral & Internal MedicinePrevalenceHumansGeostatisticsAfrica; Demographics; Geostatistics; HIV; HIV prevalence; Mapping; Spatial statistics11 Medical and Health SciencesAfrica South of the SaharaAcquired Immunodeficiency SyndromeSpatial statisticsAcquired Immunodeficiency Syndrome/epidemiologyHIVGeneral MedicineMiddle AgedSettore SECS-S/04 - DemografiaAfrica South of the Sahara/epidemiology3142 Public health care science environmental and occupational healthHIV prevalenceMapping3121 General medicine internal medicine and other clinical medicineAfricaDemographicsFemaleBMC Medicine
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Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

2020

Abstract: Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods Th…

Systems AnalysisGoutCost effectiveness030204 cardiovascular system & hematologyGlobal HealthGLOMERULAR-FILTRATION-RATEGlobal Burden of DiseaseCOST-EFFECTIVENESS0302 clinical medicineCause of DeathPrevalenceGlobal healthDiabetic NephropathiesRegistries030212 general & internal medicineSUB-SAHARAN AFRICA11 Medical and Health SciencesIncidenceMortality rate1. No povertyGeneral MedicineHälsovetenskaperGBD Chronic Kidney Disease CollaborationCKD-EPI EQUATION3. Good healthEuropeCardiovascular Diseases/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingQuality-Adjusted Life YearsLife Sciences & BiomedicineAsiaOceania195 COUNTRIESATHEROSCLEROSIS RISKCARDIOVASCULAR OUTCOMESRisk AssessmentArticle03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingRISK-FACTORGeneral & Internal MedicineEnvironmental healthHealth SciencesmedicineHumansGBD chronic kidney diseaseMortalityRisk factorRenal Insufficiency ChronicDisease burdenQMScience & TechnologyAustralasiabusiness.industryPERIPHERAL ARTERIAL-DISEASEBayes Theoremmedicine.diseaseHealth SurveysQuality-adjusted life yearRENAL-DISEASELatin AmericaYears of potential life lostAfricaNorth AmericaHuman medicinebusinessRCKidney disease
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The prevalence of onchocerciasis in Africa and Yemen, 2000-2018: a geospatial analysis.

2022

Abstract Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin disease. Predominantly endemic in parts of Africa and Yemen, preventive chemotherapy with mass drug administration of ivermectin is the primary intervention recommended for the elimination of its transmission. Methods A dataset of 18,116 geo-referenced prevalence survey datapoints was used to model annual 2000–2018 infection prevalence in Africa and Yemen. Using Bayesian model-based geostatistics, we generated spatially continuous estimates o…

Onchocerciasis; Geospatial model; Neglected tropical diseases;IvermectinYemenSettore MED/06 - Oncologia MedicaSettore MED/42 - Igiene Generale e ApplicataNigeriaBayes TheoremGeneral MedicineOnchocerciasisGhanaSettore MED/01 - Statistica MedicaGeneral & Internal MedicinePrevalenceHumansGeospatial model11 Medical and Health SciencesNeglected tropical diseasesBMC medicine
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Mapping routine measles vaccination in low- and middle-income countries

2021

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhoo…

and promotion of well-beingVacunación MasivaInternationalityDisease preventionchildren under 5 years oldGeographic MappingRural Healthmedicine.disease_causeCross-reactivity0302 clinical medicineRA0421Vaccination Refusal030212 general & internal medicineChildimmunity patternsPediatric0303 health sciencesPublic healthMultidisciplinarybiologyVaccinationUncertaintyIMMUNIZATION3142 Public health care science environmental and occupational healthCOVERAGE3. Good healthTIME3.4 VaccinesChild PreschoolInfectious diseasesA990 Medicine and Dentistry not elsewhere classifiedAntibodyEngineering sciences. TechnologyAFRICAGeneral Science & TechnologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Disease prevention ; COVID-19 ; Public health ; Infectious diseases610 Medicine & healthGlobal Vaccine Action Plan (GVAP)Local Burden of Disease Vaccine Coverage CollaboratorsArticleVaccine Related03 medical and health sciencesmeasles vaccineMeasels ; Vaccination ; Low- and middle-income countries ; Local burden of disease ; Public healthClinical ResearchmedicineHumansHealthcare DisparitiesPreschoolPROGRESS030304 developmental biologybusiness.industryMORTALITYDeveloped CountriesPreventionCommentVacunaciónUrban HealthCOVID-19Prevention of disease and conditionsVirologyCoronavirusGood Health and Well BeingCobertura de Vacunaciónbiology.proteinImmunizationbusinessMeasles
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Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease …

2020

ObjectivesThis study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study.MethodsThe GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors.ResultsIn 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39…

Maleexposure assessmentGlobal Healthmedicine.disease_causeGlobal Burden of DiseaseergonomicGBD 2016 Occupational Risk Factors Collaborators0302 clinical medicineRisk Factors1599 Other Commerce Management Tourism and ServicesNeoplasmsMETABOLIC RISKSPer capitaMedicine1506030212 general & internal medicinePublic Environmental & Occupational HealthAged 80 and overeducation.field_of_studyHuman factors and ergonomicsMiddle Aged030210 environmental & occupational health3142 Public health care science environmental and occupational health3. Good healthOccupational DiseasesCOMPARATIVE RISK-ASSESSMENTFemaleQuality-Adjusted Life YearsRisk assessmentLife Sciences & BiomedicineAdultCOUNTRIESnoiseAdolescentPopulationcancer; ergonomic; noise; respiratory tract diseases; workplaceRisk AssessmentEnvironmental & Occupational HealthAsbestosrespiratory tract disease1117 Public Health and Health ServicesYoung Adult03 medical and health sciencesAge DistributionLife ExpectancyOccupational ExposureEnvironmental healthHumanscancerDisabled PersonsSex DistributioneducationAgedScience & Technologybusiness.industryPublic Health Environmental and Occupational Health1103 Clinical SciencesTRENDSQuality-adjusted life yearrespiratory tract diseasesworkplaceSocioeconomic FactorsAttributable riskCommentaryLife expectancyWounds and InjuriesCLUSTERSbusinessLow Back PainOccupational and Environmental Medicine
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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countrie…

2015

Summary Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Methods Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause an…

MaleGerontologyNutrition and DiseaseEpidemiologyyears lived with disability Global burden of disease acute and chronic diseases countriesPrevalenceDiseaseGlobal HealthMedical and Health SciencesConduct disorderOtitis-mediaCost of IllnessResidence CharacteristicsVoeding en ZiekteEpidemiologyPrevalence80 and overGlobal health2.2 Factors relating to the physical environment2.1 Biological and endogenous factorscountriesAetiologyChildAged 80 and overMedicine(all)education.field_of_studyATTENTION-DEFICIT/HYPERACTIVITY DISORDERIncidenceMortality rateIncidence (epidemiology)Pain ResearchNeglected DiseasesAlcohol dependenceGeneral MedicineMiddle AgedGlobal burden of diseaseGlobal Burden of Disease Study 2013 CollaboratorsMental HealthInfectious DiseasesAttention deficit/Hyperactivity disorderBurden of IllnessChild PreschoolAcute DiseaseFemaleLife Sciences & BiomedicineAdultmedicine.medical_specialtyAdolescentGBD 2013Populationacute and chronic diseasesYoung AdultMental-disordersAge DistributionMedicine General & InternalWeightsGeneral & Internal MedicinemedicineHumansLife ScienceDisabled PersonsSex DistributionPreschooleducationDeveloping CountriesVLAGAgedScience & Technologybusiness.industryDeveloped CountriesCutaneous LeishmaniasisInfant NewbornInfantHealth outcomesNewbornmedicine.diseaseComorbidityBrain Disordersyears lived with disabilityGood Health and Well BeingDisease injury incidence prevalence YLDs GBD 2010Chronic DiseaseWounds and Injuriesbusiness2.4 Surveillance and distributionIron-deficiencyDemography
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