showing 2 related works from this author
NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer
2019
γδ T cells account for a large fraction of human intestinal intraepithelial lymphocytes (IELs) endowed with potent anti-tumor activities. However, little is known about their origin, phenotype and clinical relevance in colorectal cancer (CRC). To determine γδ IEL gut-specificity, homing and functions, γδ T cells were purified from human healthy blood, lymph nodes, liver, skin, intestine either disease-free or affected by CRC or generated from thymic precursors. The constitutive expression of NKp46 specifically identifies a new subset of cytotoxic Vδ1 T cells representing the largest fraction of gut-resident IELs. The ontogeny and gut-tropism of NKp46pos/Vδ1 IELs depends both on distinctive …
Supersymmetric Indices of 3d S-fold SCFTs
2019
Enhancement of global symmetry and supersymmetry in the infrared is one of the most intriguing phenomena in quantum field theory. We investigate such phenomena in a large class of three dimensional superconformal field theories, known as the S-fold SCFTs. Supersymmetric indices are computed for a number of theories containing small rank gauge groups. It is found that indices of several models exhibit enhancement of supersymmetry at the superconformal fixed point in the infrared. Dualities between S-fold theories that have different quiver descriptions are also analysed. We explore a new class of theories with a discrete global symmetry, whose gauge symmetry in the quiver has a different glo…