0000000000741386

AUTHOR

I. Toirac

showing 2 related works from this author

A possible association between the CCK-AR gene and persistent auditory hallucinations in schizophrenia.

2004

AbstractRecent studies have suggested that DNA variations in the CCK-AR gene might predispose individuals to schizophrenia and particularly to auditory hallucinations (AH). The aim of this study is to assess the association between AH, using a specific scale for AH in schizophrenia (PSYRATS), and the CCK-AR polymorphism at 779 in a Spanish sample. A total of 105 DSM-IV schizophrenic patients with AH and 93 unrelated controls were studied. Twenty-two patients were considered as persistent auditory hallucinators, which showed similar clinical and demographic characteristic than patients with episodic AH, but with the exception of the PSYRATS values. The persistent AH group showed an excess of…

AdultMalemedicine.medical_specialtyPsychosisPeriodicityGenotypeHallucinationsSeverity of Illness IndexGenetic determinismLinkage Disequilibrium03 medical and health sciences0302 clinical medicineGene FrequencyInternal medicineSurveys and QuestionnairesSeverity of illnessmedicineHumansAlleleSex DistributionPsychiatryAllele frequencyGenetic associationDNA PrimersDemographyAuditory hallucinationPolymorphism Geneticmedicine.diseaseIntrons030227 psychiatryReceptor Cholecystokinin ADiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthEndocrinologySchizophreniaSchizophreniaFemalemedicine.symptomPsychology030217 neurology & neurosurgeryEuropean psychiatry : the journal of the Association of European Psychiatrists
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Association between CCK-AR gene and schizophrenia with auditory hallucinations

2007

[Objective]: Previous studies on a possible association between CCK-AR polymorphisms and schizophrenia have been controversial. The aim of the present study was to assess a potential association between schizophrenic patients with auditory hallucinations and polymorphisms of the CCK-AR gene.

medicine.medical_specialtyGenotypeHallucinationsSingle-nucleotide polymorphismAuditory hallucinationsRegulatory Sequences Nucleic Aciddigestive systemPolymorphism Single NucleotideGene FrequencyReference ValuesInternal medicineGenotypeGene expressionGeneticsmedicineHumansSNPCCK-AR geneAllelePsychiatryGeneBiological PsychiatryGenetics (clinical)DNA Primersbusiness.industrydigestive oral and skin physiologyHaplotypeDNAmedicine.diseaseReceptor Cholecystokinin APsychiatry and Mental healthEndocrinologySchizophreniaSchizophreniaSchizophrenic Psychologybusinesshormones hormone substitutes and hormone antagonistsPsychiatric Genetics
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