0000000000749714

AUTHOR

Thomas Bertsch

showing 2 related works from this author

Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis.

2003

Intestinal ischaemia is a major complication of shock syndromes causing translocation of bacteria and endotoxins and multiple organ failure in intensive care patients. The present study was designed to use microdialysis as a tool to monitor intestinal ischaemia after cardiac arrest and resuscitation in pigs. For this purpose, microdialysis probes were implanted in pig jejunal wall, peritoneum, skeletal muscle and brain, and interstitial fluid was obtained during circulatory arrest (induced by ventricular fibrillation) and after return of spontaneous circulation (ROSC). Cardiac arrest for 4 min caused a prolonged (60 min) reduction of blood flow in jejunal wall, muscle and brain as determine…

medicine.medical_specialtyMicrodialysisResuscitationTime FactorsSwinemedicine.medical_treatmentMicrodialysisIschemiaGlutamic AcidEmergency NursingReturn of spontaneous circulationCholineIschemiaInternal medicineIntensive caremedicineAnimalsCardiopulmonary resuscitationLactic AcidIntestinal MucosaMuscle Skeletalbusiness.industrySkeletal muscleBrainmedicine.diseaseCardiopulmonary ResuscitationHeart ArrestIntestinesEndocrinologymedicine.anatomical_structureGlucoseAnesthesiaVentricular fibrillationEmergency MedicinePeritoneumCardiology and Cardiovascular MedicinebusinessExtracellular SpaceResuscitation
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Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study.

2023

Background and Purpose: This randomized study aimed to evaluate whether the use of a stroke clock demanding active feedback from the stroke physician accelerates acute stroke management. Methods: For this randomized controlled study, a large-display alarm clock was installed in the computed tomography room, where admission, diagnostic work-up, and intravenous thrombolysis occurred. Alarms were set at the following target times after admission: (1) 15 minutes (neurological examination completed); (2) 25 minutes (computed tomography scanning and international normalized ratio determination by point-of-care laboratory completed); and (3) 30 minutes (intravenous thrombolysis started). The resp…

Malemedicine.medical_specialtythrombolysisTime FactorsComputed Tomography Angiographymedicine.medical_treatment610law.inventionBrain IschemiaFeedbackPhysical medicine and rehabilitationRandomized controlled trialFibrinolytic AgentslawmedicineHumansActive feedbackThrombolytic TherapyAcute managementStrokeAcute strokeAgedAdvanced and Specialized NursingAged 80 and overbusiness.industryDisease ManagementThrombolysisMiddle Agedmedicine.diseaseStrokethrombectomyTissue Plasminogen ActivatorFemaleNeurology (clinical)Cardiology and Cardiovascular Medicinebusinessacute managementTomography X-Ray ComputedStroke
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