0000000000749748

AUTHOR

Giuseppe Antonio Malfa

showing 4 related works from this author

The Sicilian wild cabbages as biological resources: taxonomic update and a review on chemical constituents and biological activities

2020

Considering the growing interest that wild brassicas have as sources of bioactive molecules as well as a genetic resource, the authors review and update the taxonomy of Brassica sect. Brassica, limited to the native flora of Sicily, an island considered to be an active diversification center for the group of species of the aforementioned section. Regarding the taxonomic aspects, Brassica tardarae is here considered a subspecies of B. rupestris; the distinction at the subspe- cific level of B. raimondoi, a critical taxon included in B. incana, is also confirmed. In addition, two new subspecies are proposed, respectively in B. incana and B. rupestris. The taxonomic information relating to the…

EcologySettore BIO/02 - Botanica SistematicaPhytochemicalsPlant ScienceBiologylanguage.human_languageVascular floraChemical constituentsBrassicaceaelanguageGlucosinolates. SicilySettore BIO/15 - Biologia FarmaceuticaSicilianBrassica sect. BrassicaTaxonomyvascular flora Brassica sect. Brassica Brassicaceae taxonomy phytochemicals glucosinolates. Sicily
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Altilix® Supplement Containing Chlorogenic Acid and Luteolin Improved Hepatic and Cardiometabolic Parameters in Subjects with Metabolic Syndrome: A 6…

2019

The objective was to evaluate the effects of 6 months of supplementation with Altilix&reg

0301 basic medicineSettore MED/09 - Medicina Internacynaragenetic structuresPlacebo-controlled study030204 cardiovascular system & hematologySettore BIO/09 - FisiologiaGastroenterology0302 clinical medicineDiabetes mellitusimmune system diseasescardiovascular diseasehemic and lymphatic diseasesBrachial arteryLuteolinNutrition and Dieteticsdiabetes mellituFatty liverhemic and immune systemsDietary supplementsMetabolic syndromeCardiovascular diseasesLivertype 2diabetes mellitusChlorogenic Acidlcsh:Nutrition. Foods and food supplymedicine.medical_specialtyWaistlcsh:TX341-641chemical and pharmacologic phenomenaCynaraPlacebometabolic syndromedietary supplements03 medical and health sciencesDouble-Blind MethodInternal medicineDiabetes mellitusmedicine.arterymedicinebusiness.industrynon-alcoholic fatty liver diseasemedicine.diseasecardiovascular diseases030104 developmental biologydietary supplementSteatosisMetabolic syndromebusinessFood ScienceNon-alcoholic fatty liver disease
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Effects of essential oils and selected compounds from Lamiaceae family as adjutants on the treatment of subjects with periodontitis and cardiovascula…

2021

Essential oils from different plant species were found to contain different compounds exhibiting anti-inflammatory effects with the potential to be a valid alternative to conventional chemotherapy that is limited in long-term use due to its serious side effects. Generally, the first mechanism by which an organism counteracts injurious stimuli is inflammation, which is considered a part of the innate immune system. Periodontitis is an infectious and inflammatory disease caused by a dysbiosis in the subgingival microbiome that triggers an exacerbated immune response of the host. The immune–inflammatory component leads to the destruction of gingival and alveolar bone tissue. The main anti-infl…

TechnologyQH301-705.5QC1-999VolatileInflammationDiseaseheart disease risk factorsoilvolatileProinflammatory cytokineImmune systemCarvacrolmedicineperiodontitiGeneral Materials ScienceMicrobiomeBiology (General)PeriodontitisperiodontitisQD1-999InstrumentationHeart disease risk factorsInflammationFluid Flow and Transfer ProcessesPeriodontitisEucalyptolInnate immune systembusiness.industrySettore BIO/16 - Anatomia UmanaTPhysicsProcess Chemistry and TechnologyGeneral EngineeringoilsEngineering (General). Civil engineering (General)medicine.diseaseComputer Science ApplicationsChemistryinflammationImmunologyRosmarinus officinalisTA1-2040medicine.symptombusinessOilsDysbiosis
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Chemical, Antioxidant and Biological Studies of Brassica incana subsp. raimondoi (Brassicaceae) Leaf Extract

2023

Brassica incana subsp. raimondoi is an endemic taxon present in a restricted area located on steep limestone cliffs at an altitude of about 500 m a.s.l. in eastern Sicily. In this research, for the first time, studies on the phytochemical profile, the antioxidant properties in cell-free and cell-based systems, the cytotoxicity on normal and cancer cells by 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay, and on Artemia salina Leach, were performed. The total phenolic, flavonoid, and condensed tannin contents of the leaf hydroalcoholic extract were spectrophotometrically determined. Ultra-performance liquid chromatography—tandem mass spectrometer (UPLC-MS/MS) analysi…

H2O2Pharmaceutical SciencecabbageHPLC/DADAnalytical ChemistryDrug Discoverybotanicalsoxidative stressSettore BIO/15 - Biologia Farmaceutica<i>Artemia salina</i> LeachPhysical and Theoretical ChemistrypolyphenolsArtemia salina Leachnutraceuticalsoxidative streH<sub>2</sub>O<sub>2</sub>Settore BIO/02 - Botanica SistematicaOrganic ChemistrycarotenoidsROSH2 O2carotenoidbotanicalpolyphenolcabbagesUPLC-MS/MSChemistry (miscellaneous)Molecular MedicinenutraceuticalMolecules
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