Author: Arturo Tortosa

0000000000749884

AUTHOR

Arturo Tortosa

Organocatalytic enantioselective functionalization of indoles in the carbocyclic ring with cyclic imines

[EN] An organocatalytic enantioselective functionalization in the carbocyclic ring of indoles with benzoxathiazine 2,2-dioxides is described using a quinine-derived bifunctional organocatalyst. This aza-Friedel-Crafts reaction provides 4-indolyl, 5-indolyl and 7-indolyl sulfamidate derivatives in good yields (up to 99%) and with moderate to high enantioselectivities (up to 86% ee).

research product

CCDC 1846586: Experimental Crystal Structure Determination

Related Article: Carlos Vila, Arturo Tortosa, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro|2019|New J.Chem.|43|130|doi:10.1039/C8NJ05577G

research product

CCDC 1875758: Experimental Crystal Structure Determination

Related Article: Carlos Vila, Arturo Tortosa, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro|2019|New J.Chem.|43|130|doi:10.1039/C8NJ05577G

research product

PEPhysical Sciences and Engineering
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