0000000000750992

AUTHOR

Fernando Simón

showing 5 related works from this author

Proteomic analysis of the somatic and surface compartments from Dirofilaria immitis adult worms.

2014

31 páginas, 1 tabla, 4 figuras.-- The definitive version is available at http://www.elsevier.com

MaleProteomicsPathologymedicine.medical_specialtyProteomeSomatic cellDirofilaria immitisDirofilaria immitisProteomicsGenomeMicrobiologyTranscriptomeImmune systemmedicineParasite hostingAnimalsSomaticCATSGeneral VeterinarybiologyGeneral MedicineHelminth Proteinsbiology.organism_classificationSurfaceProtein TransportGene Expression RegulationAntigens SurfaceParasitologyFemaleVeterinary parasitology
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Human subcutaneous dirofilariasis, Russia

2007

We report 14 cases of human subcutaneous dirofilariasis caused by Dirofilaria repens, diagnosed from February 2003 through July 2004, in patients from Rostov-on-Don, Russia. Serologic analysis showed evidence of high risk of exposure to D. repens. Surveillance studies on prevalence and prevention effectiveness of canine infection are needed to control this emerging zoonosis.

AdultMaleMicrobiology (medical)Pathologymedicine.medical_specialtyEpidemiologyAntibodies HelminthSubcutaneous dirofilariasisserologylcsh:MedicineRepensSerologyRussialcsh:Infectious and parasitic diseaseshistologyDirofilariasismedicineHumansHelminthsIn patientlcsh:RC109-216Skin Diseases ParasiticHuman subcutaneous dirofilariasisAgedbiologybusiness.industryZoonosislcsh:RDispatchMiddle Agedmedicine.diseasebiology.organism_classificationDermatologyDirofilaria repensInfectious DiseasesPCRFemaleDirofilaria repensDirofilariasisbusiness
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rDNA Sequences of <I>Anopheles</I> Species from the Iberian Peninsula and an Evaluation of the 18S rRNA Gene as Phylogenetic Marker in An…

2006

The complete 18S rDNA and internal transcribed spacer (ITS)-2 rDNA sequences were obtained from Anopheles atroparvus Van Thiel and Anopheles plumbeus Stephens from two areas of Spain. The number of nucleotide differences in the 18S rDNA of the two species is high compared with differences in the same gene of other invertebrate vectors. In Anopheles, short 18S rDNA sequences are richer in AT than the longer sequences, which are richer in GC and include extremely GC-biased expanded regions. Four small regions in the variable regions V4 and V7 contain the majority of nucleotide differences. The results did not support the use of partial sequences for relationship analyses. Genetic distances an…

GeneticsGeneral VeterinaryPhylogenetic treeSequence alignmentBiology16S ribosomal RNA18S ribosomal RNAInfectious DiseasesGenetic markerPhylogeneticsInsect ScienceParasitologyInternal transcribed spacerRibosomal DNAJournal of Medical Entomology
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Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneit…

2019

15 páginas, 5 figuras y 1 tabla

0301 basic medicineAntifibrinolyticContact systemmedicine.drug_classmedicine.medical_treatment030231 tropical medicineBradykininInflammationNeurological disorderFibrinolysis systemProteomic and mass spectrometry analysesBlood–brain barrierFasciola excretome/secretomeProinflammatory cytokine03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBlood-brain barrier leakageFibrinolysismedicineIndicators and preventionAcute and chronic phasesPlasminogen-binding proteinsFasciolabiologyHuman fascioliasis030108 mycology & parasitologymedicine.diseasebiology.organism_classificationInfectious Diseasesmedicine.anatomical_structurechemistryImmunologyAnimal Science and ZoologyParasitologymedicine.symptomNeurological disordersResearch Article
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Angiogenic response in an in vitro model of dog microvascular endothelial cells stimulated with antigenic extracts from Dirofilaria immitis adult wor…

2019

Abstract Background Angiogenesis can occur under pathological conditions when stimuli such as inflammation, vascular obstruction or hypoxia exist. These stimuli are present in cardiopulmonary dirofilariosis (Dirofilaria immitis). The aim of this study was to analyze the capacity of D. immitis antigens to modify the expression of angiogenic factors and trigger the formation of pseudocapillaries (tube-like structures) in an in vitro model of endothelial cells. Methods The expression of VEGF-A, sFlt, mEndoglin and sEndoglin in cultures of canine microvascular endothelial cells stimulated with extract of adult worms of D. immitis obtained from an untreated dog (DiSA) and from a dog treated for …

0301 basic medicineDirofilaria immitis antigenic extractsEndotheliumAngiogenesisCell SurvivalDirofilaria immitis030231 tropical medicineCellNeovascularization PhysiologicCanine microvascular endothelial cellsDirofilaria immitisBiologylcsh:Infectious and parasitic diseasesAndrologyWolbachia amount03 medical and health sciences0302 clinical medicineDogsAntigenmedicineAnimalslcsh:RC109-216Cells CulturedInflammationMatrigelAntigens BacterialAngiogenic factorsResearchEndothelial CellsParasitologia veterinàriabiology.organism_classificationIn vitroCapillariesAngiogènesi030104 developmental biologyInfectious Diseasesmedicine.anatomical_structureCell cultureAntigens HelminthParasitologyPseudocapillaries formationWolbachia
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