0000000000754127

AUTHOR

S. Spadaro

showing 8 related works from this author

Gδ covers of compact spaces

2018

We solve a long standing question due to Arhangel'skii by constructing a compact space which has a Gδ cover with no continuum-sized (Gδ)-dense subcollection. We also prove that in a countably compact weakly Lindelöf normal space of countable tightness, every Gδ cover has a -sized subcollection with a Gδ-dense union and that in a Lindelöf space with a base of multiplicity continuum, every Gδ cover has a continuum sized subcover. We finally apply our results to obtain a bound on the cardinality of homogeneous spaces which refines De La Vega's celebrated theorem on the cardinality of homogeneous compacta of countable tightness.

Cardinal function Gδ-cover Lindelof degree Homogeneous spaceSettore MAT/03 - Geometria
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Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (Intensive Care M…

2018

The members of the LUNG SAFE Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for this error.

Critical Care and Intensive Care Medicine
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Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

2018

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initial…

MaleARDSmedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]ARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS;Critical Care and Intensive Care Medicineassisted ventilation0302 clinical medicineRisk Factors030212 general & internal medicinerisk factor AdultTidal volumecomparative studyeducation.field_of_studyRespiratory Distress SyndromeMortality rateRemission Inductiontidal volumeARDS reassessment; ARDS Survival; Berlin criteria ARDS; Persisting ARDS; Critical Care and Intensive Care MedicineARDS reassessmentartificial ventilationclinical trialimmunosuppressive treatmentadult respiratory distress syndromeMiddle AgedARDS SurvivalMonte Carlo methodmedicine.anatomical_structureclassificationpositive end expiratory pressureCardiologyDisease ProgressionSOFA scoredisease severityFemaleAdultmedicine.medical_specialtyPopulationdisease classificationArticleNO03 medical and health sciencesremissionlength of stayAnesthesiologyInternal medicinemedicinepneumoniaSequential Organ Failure Assessment ScoreHumanshumaneducationAgedMechanical ventilationhospital mortalityLungbusiness.industryRisk Factordisease associationRespiratory Distress Syndrome AdultPersisting ARDSmedicine.diseasemajor clinical studymortalityRespiration Artificialbreathing rate030228 respiratory systemdisease exacerbationBerlin criteria ARDSbusinessIntensive care medicine
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The PROVENT-C19 registry: A study protocol for international multicenter SIAARTI registry on the use of prone positioning in mechanically ventilated …

2022

Background The worldwide use of prone position (PP) for invasively ventilated patients with COVID-19 is progressively increasing from the first pandemic wave in everyday clinical practice. Among the suggested treatments for the management of ARDS patients, PP was recommended in the Surviving Sepsis Campaign COVID-19 guidelines as an adjuvant therapy for improving ventilation. In patients with severe classical ARDS, some authors reported that early application of prolonged PP sessions significantly decreases 28-day and 90-day mortality. Methods and analysis Since January 2021, the COVID19 Veneto ICU Network research group has developed and implemented nationally and internationally the “PRO…

Multidisciplinaryprone positionrespiratory failureCOVID-19PLOS ONE
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The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a po…

2021

Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries.…

Driving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanics;Lung DiseasesMaleLaparoscopic surgery[SDV]Life Sciences [q-bio]medicine.medical_treatmentLaparoscopic surgeryCohort StudiesPositive-Pressure RespirationPostoperative Complications0302 clinical medicinePneumoperitoneum030202 anesthesiologyPneumoperitoneumAbdomenClinical endpointPerioperative ventilationMiddle Aged3. Good healthDriving pressure Laparoscopic surgery Laparoscopy PEEP Perioperative ventilation Pneumoperitoneum Protective ventilation Respiratory mechanicsDriving pressureFemaleResearch ArticleCohort studyProtective ventilationAdultmedicine.medical_specialtyAnestesi och intensivvårdRespiratory mechanicsAnesthesia GeneralNOlcsh:RD78.3-87.303 medical and health sciencesmedicineHumansPropensity ScoreAdverse effectPEEPAgedRetrospective StudiesDriving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanicsAnesthesiology and Intensive Carebusiness.industryKirurgi030208 emergency & critical care medicineOdds ratiomedicine.diseaseRespiration ArtificialSurgeryAnesthesiology and Pain Medicinelcsh:AnesthesiologyRelative riskSurgeryLaparoscopyDriving pressure ; Laparoscopic surgery ; Laparoscopy ; PEEP ; Perioperative ventilation ; Pneumoperitoneum ; Protective ventilation ; Respiratory mechanics.businessAbdominal surgery
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Erratum to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC‑GLOSSARI): a multicenter, multinational, 14-day inception coh…

2018

In both the original publication (DOI 10.1007/s00134-015-4206-2) and the first erratum (DOI 10.1007/s00134-016-4317-4), the members of the IC-GLOSSARI Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for these errors and is pleased to list the members of the groups here: (Table presented.).

Critical Care and Intensive Care Medicine
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Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort…

2021

Abstract Background The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic value of frailty in this context. Methods We analysed data from two multicentre prospective cohort studies which enrolled intensive care unit patients ≥ 80 years old in 26 countries. The primary outcome was mortality within 30-days from admission to the ICU. Logistic regression models for…

MaleShort term mortalityCritical Care and Intensive Care MedicineCohort Studies0302 clinical medicinekwetsbaarheidMedicine and Health Sciences80 and overMedicine610 Medicine & healthProspective cohort studyCorrelation of Data11 Medical and Health SciencesAged 80 and overOUTCOMESIntensive care unitsFrailtyVIP1Aged&nbspMedical emergencies. Critical care. Intensive care. First aidScale (social sciences)Femaleprospectief onderzoekLife Sciences & BiomedicineCRITICALLY-ILL PATIENTS 80 and overStudy groupsmedicine.medical_specialtyAnestesi och intensivvård80 jaar en ouder610 Medicine & healthINTENSIVE-CAREBED AVAILABILITYNO03 medical and health sciencesCritical Care MedicineIntensive caresterfteGeneral & Internal MedicineHumansIntensive care units; Aged; 80 and over; Frailty; Prospective studies; MortalityIn patientddc:610Aged 80 and over; Frailty; Intensive care units; Mortality; Prospective studies; Aged 80 and over; Cohort Studies; Correlation of Data; Female; Frailty; Humans; Intensive Care Units; Logistic Models; Male; Mortality; Prospective StudiesMortalityAgedScience & TechnologyAnesthesiology and Intensive Carebusiness.industryRC86-88.9Research030208 emergency & critical care medicineADULTSAged 80 and over; Frailty; Intensive care units; Mortality; Prospective studies;Emergency & Critical Care MedicineLogistic Models030228 respiratory systemintensivecareafdelingenAged 80 and overCritical illnessEmergency medicineVIP2 study group&nbspCRITICAL ILLNESSbusinessProspective studies
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Association between preoperative evaluation with lung ultrasound and outcome in frail elderly patients undergoing orthopedic surgery for hip fracture…

2021

Abstract Background Hip fracture is one of the most common orthopedic causes of hospital admission in frail elderly patients. Hip fracture fixation in this class of patients is considered a high-risk procedure. Preoperative physical examination, plasma natriuretic peptide levels (BNP, Pro-BNP), and cardiovascular scoring systems (ASA-PS, RCRI, NSQIP-MICA) have all been demonstrated to underestimate the risk of postoperative complications. We designed a prospective multicenter observational study to assess whether preoperative lung ultrasound examination can predict better postoperative events thanks to the additional information they provide in the form of “indirect” and “direct” cardiac an…

medicine.medical_specialtyR895-920Physical examination030204 cardiovascular system & hematologylaw.inventionNOMedical physics. Medical radiology. Nuclear medicine03 medical and health sciences0302 clinical medicineRandomized controlled triallawmedicineRadiology Nuclear Medicine and imaging030212 general & internal medicineProspective cohort studylung ultrasoundHip surgeryHip fractureRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryInterventional radiologymedicine.diseaseSurgeryOrthopedic surgeryObservational studyOriginal Articlebusiness
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