0000000000755207

AUTHOR

Lucia Brodosi

0000-0002-7735-7847

showing 3 related works from this author

Management of Diabetes in Candidates for Liver Transplantation and in Transplant Recipients.

2021

Diabetes is common in patients wait-listed for liver transplantation due to end-stage liver disease or to hepatocellular cancer as well as in post-transplant phase (post-transplantation diabetes mellitus-PTDM). In both conditions the presence of diabetes severely affects disease burden and long-term clinical outcomes; careful monitoring and appropriate treatment are pivotal to reduce cardiovascular events and graft and recipients' death. We thoroughly reviewed the epidemiology of diabetes in the transplant setting and the different therapeutic options, from lifestyle intervention to antidiabetic drug use - including the most recent drug classes available - and to the inclusion of bariatric …

medicine.medical_specialtyGLP-1 receptor agonistmedicine.medical_treatmentposttransplantation diabetes mellituDiseaseHypoglycemiaLiver transplantationLiver diseaseDiabetes mellitusmedicineDiabetes MellitusDPP-4 inhibitorHumansHypoglycemic AgentsIntensive care medicineDisease burdenTransplantationbusiness.industrySGLT-2 inhibitorsFatty livermedicine.diseaseDiabetes NAFLD Liver transplantationHypoglycemiaTransplant RecipientsLiver TransplantationTransplantationbusinessTransplantation
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An internet-based approach for lifestyle changes in patients with NAFLD: Two-year effects on weight loss and surrogate markers

2018

Background & Aims Interventions aimed at lifestyle changes are pivotal for the treatment of non-alcoholic fatty liver disease (NAFLD), and web-based programs might help remove barriers in both patients and therapists. Methods In the period 2010–15, 716 consecutive NAFLD cases (mean age, 52; type 2 diabetes, 33%) were treated in our Department with structured programs. The usual protocol included motivational interviewing and a group-based intervention (GBI), chaired by physicians, dietitians and psychologists (five weekly meetings, n = 438). Individuals who could not attend GBI entered a web-based intervention (WBI, n = 278) derived from GBI, with interactive games, learning tests, motivati…

Liver CirrhosisMalemedicine.medical_specialtyMotivational interviewingPsychological interventionType 2 diabetesDisease03 medical and health sciences0302 clinical medicinePatient Education as TopicWeight lossNon-alcoholic Fatty Liver DiseaseInternal medicineWeight LossmedicineHumansNAFLD progression030212 general & internal medicineExerciseLife StyleAged2. Zero hungerInternetHepatologybusiness.industryPhysical activityFatty liverLiver enzymeAlanine TransaminaseHepatologyMiddle Agedmedicine.diseaseDiet; Liver enzymes; NAFLD progression; Physical activity; HepatologyTelemedicineLiver enzymes3. Good healthDietLogistic Models030211 gastroenterology & hepatologyFemalemedicine.symptombusinessBody mass indexBiomarkers
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Lifestyle Changes for the Treatment of Nonalcoholic Fatty Liver Disease - A 2015-19 Update.

2020

Background: Lifestyle interventions aimed at weight loss have been associated with improved liver enzymes, reduced intrahepatic triglyceride content, and improved histology (including reduced fibrosis stage). Objective: To revise the evidence on the beneficial effects of lifestyle changes accumulated since 2015, following the publication of the pivotal Cuban experience with histologic outcome. Methods: A PubMed search covering the period 2015 to July 2019 was carried out. All retrieved references were analyzed and double-checked by authors. Results: 20 new studies were identified; in addition, two relevant studies provided new evidence. Thirteen studies were classified as randomized, contr…

Liver Cirrhosismedicine.medical_specialtyFibrosiLiver CirrhosiPopulationMotivational interviewingInformation technology01 natural sciencesTriglycerideElectronic mail03 medical and health sciencesWeight lossFood intakeNon-alcoholic Fatty Liver DiseaseDrug DiscoveryNonalcoholic fatty liver diseaseWeight LossmedicineHumanseducationLife StyleTriglycerides030304 developmental biologyRandomized Controlled Trials as TopicPharmacology0303 health scienceseducation.field_of_studyInternetText MessagingCirrhosiElectronic Mailbusiness.industrymedicine.diseasePhysical activity steatosiWeight Lo0104 chemical sciencesTelephone010404 medicinal & biomolecular chemistryObservational Studies as TopicBehavior therapyCohortPhysical therapyObservational Studies as TopicObservational studymedicine.symptomBehavior therapy Cirrhosis Fibrosis Food intake Information technology Physical activity steatosisbusinessHumanCurrent pharmaceutical design
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