0000000000757023

AUTHOR

Rosaria Farruggio

showing 4 related works from this author

Sex hormones modulate inflammatory mediators produced by macrophages.

1999

Lipopolysaccharidesmedicine.medical_specialtyNitric oxide biosynthesisReceptors EstradiolNitric OxideGeneral Biochemistry Genetics and Molecular BiologyCell LineHistory and Philosophy of ScienceInternal medicinemedicineAnimalsTestosteroneReceptorEstradiolbusiness.industryTumor Necrosis Factor-alphaGeneral NeuroscienceMacrophagesTumor Necrosis Factor alpha biosynthesisAndrogen MetabolismInterleukin-10EndocrinologyCell cultureReceptors AndrogenInflammation MediatorsbusinessHormoneAnnals of the New York Academy of Sciences
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Steroid-growth factor interaction in human prostate cancer. 2. Effects of transforming growth factors on androgen metabolism of prostate cancer cells

1996

The ability of human prostate cancer cells to metabolize androgens was assessed through administration of physiological concentration (0.5-10 nM) of tritiated testosterone (T) as precursor and one-step analysis of both T degradation and products' formation by reverse-phase HPLC and on-line radioactive detection after either 24 h or 72 h incubation. Overall, different prostate cancer cells degraded T quite differently, favoring alternatively reductive or oxidative metabolic pathways. In particular, both LNCaP and DU145 cells retained high levels of unconverted T, with a limited production of androstenedione and its 17-keto derivatives and relatively high amounts of dihydrotestosterone (DHT) …

Malemedicine.medical_specialtymedicine.drug_classClinical BiochemistryBiologyurologic and male genital diseasesBiochemistrychemistry.chemical_compoundEndocrinologyDU145Transforming Growth Factor betaInternal medicineLNCaPTumor Cells CulturedmedicineHumansMolecular BiologyTestosteronePharmacologyAndrosteroneOrganic ChemistryProstatic NeoplasmsTransforming Growth Factor alphaAndrogenEndocrinologychemistryDihydrotestosteroneCancer cellAndrogensmedicine.drugTransforming growth factorSteroids
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Multiple Estrogen Function in Human Prostate Cancer Cells

1996

MalePCA3Oncologymedicine.medical_specialtyNeoplasms Hormone-DependentCell divisionmedicine.drug_classGeneral Biochemistry Genetics and Molecular BiologyHistory and Philosophy of ScienceHeat shock proteinInternal medicineTumor Cells CulturedAnimalsHumansMedicineHeat-Shock Proteinsbusiness.industryCadherinGeneral NeuroscienceProstatic NeoplasmsCancerEstrogensProstate-Specific AntigenCadherinsmedicine.diseaseRatsProstate-specific antigenReceptors EstrogenEstrogenCancer cellAndrogensbusinessCell DivisionAnnals of the New York Academy of Sciences
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Truncated Form of beta-Catenin and Reduced Expression of Wild-Type Catenins Feature HepG2 Human Liver Cancer Cells

2000

Pathologymedicine.medical_specialtyCarcinoma HepatocellularBeta-cateninbiologyChemistryGeneral NeuroscienceLiver NeoplasmsWild typemedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyCell biologyCytoskeletal ProteinsHuman liver cancerHistory and Philosophy of ScienceCateninTrans-Activatorsbiology.proteinmedicineCarcinomaHumansTrans-Activatorsbeta CateninAnnals of the New York Academy of Sciences
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