0000000000761650

AUTHOR

A. Spera

showing 2 related works from this author

Transitional cell carcinoma of endometrium: a case report of rare pure form

2018

Transitional cell carcinoma is a very rare histological subtype of endometrial cancer, with only 18 cases described in literature. Ovary represents the most common site where it accounts for 2% of all ovarian cancers. Due to the rarity of this disease, current management is controversial and includes various approaches, mostly described in the adjuvant setting, both radiotherapy and chemotherapy alone or in combination. Here, we report a case of a 65-year-old patient who underwent adjuvant vaginal brachytherapy for an endometrial transitional cell carcinoma. The patient was treated with radical total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO), without lymph-node sa…

medicine.medical_specialtymedicine.medical_treatmentBrachytherapybrachytherapylcsh:MedicineCase ReportEndometrial Transitional Cell CarcinomaEndometrium03 medical and health sciences0302 clinical medicinetransitional cell carcinomamedicineRadiology Nuclear Medicine and imagingendometriumChemotherapyGenitourinary systembusiness.industryEndometrial cancergynecologylcsh:Rmedicine.diseaseRadiation therapymedicine.anatomical_structureTransitional cell carcinomaOncology030220 oncology & carcinogenesisRadiologybusiness030217 neurology & neurosurgeryJournal of Contemporary Brachytherapy
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Moderate hypofractionated helical tomotherapy for localized prostate cancer: preliminary report of an observational prospective study.

2019

Objective: To report preliminary findings of a phase II study exploring the clinical outcomes of moderate hypofractionated radiotherapy performed with helical tomotherapy (HT) using computed tomography–magnetic resonance imaging–based planning for localized prostate cancer. Methods: The phase II prospective study received ethics approval from our institutional ethics committee. A dose of 60 Gy/20 fractions for low–intermediate risk prostate cancer by means of HT was explored. Primary endpoints of the study were acute and late gastrointestinal (GI) and genitourinary (GU) toxicities. Secondary endpoints were quality of life and biochemical-free survival. Results: A total of 35 patients were i…

Hypofractionated RadiotherapyMaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmenttomotherapyPhases of clinical researchTomotherapy030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancer0302 clinical medicinePreliminary reportProstatemedicineBiomarkers TumorHumansProspective StudiesNeoplasm MetastasisProspective cohort studyRadiometryProstate hypofractionation tomotherapyAgedNeoplasm StagingAged 80 and overhypofractionationbusiness.industryRadiotherapy Planning Computer-AssistedProstateProstatic NeoplasmsGeneral MedicineMiddle Agedmedicine.diseasehypofractionation; Prostate; tomotherapymedicine.anatomical_structureTreatment OutcomeOncology030220 oncology & carcinogenesisQuality of LifeObservational studyRadiation Dose HypofractionationRadiologyRadiotherapy Intensity-ModulatedbusinessFollow-Up StudiesTumori
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