0000000000773316
AUTHOR
M. Teresa Musmeci
Interactions of organotins with biological systems
The bonding and structure in the environments of tin atoms in organotin-biological molecules has been investigated by 119Sn Mossbauer spectroscopy, mainly through the rationalization of the nuclear quadrupole splitting parameter by pointcharge model approaches. Organotin moieties R2SnIV and R3SnIV (R = Me, nBu, Ph) generally assume trigonal-bipyramidal type configurations in membranes of human erythrocytes, when incubated with whole erythrocytes and erythrocyte ghosts at the level of micromolar (μmol dm−3) organotin per mg of membrane protein. Corresponding structures are assumed by Me2SnIV and Me3SnIV in the cytoplasm. Ethanolic Me2SnCl2 yielded distorted trans-octahedral species when reac…
Oxidized respiratory molecules induced in vivo by nitrite in Pontodrilus littoralis (oligochaeta)
Abstract 1. The in vivo effect of nitrite has been investigated in Pontodrilus littoralis. 2. Exposure of the animals at nitrite concentrations (0.05–0.1%) produced methaemoglobin and hemichromes. 3. Disappearance of oxidized forms was obtained when normal rearing conditions were restored. 4. Longer exposure to higher nitrite concentrations produced irreversible oxidized forms.