0000000000773316

AUTHOR

M. Teresa Musmeci

showing 2 related works from this author

Interactions of organotins with biological systems

1992

The bonding and structure in the environments of tin atoms in organotin-biological molecules has been investigated by 119Sn Mossbauer spectroscopy, mainly through the rationalization of the nuclear quadrupole splitting parameter by pointcharge model approaches. Organotin moieties R2SnIV and R3SnIV (R = Me, nBu, Ph) generally assume trigonal-bipyramidal type configurations in membranes of human erythrocytes, when incubated with whole erythrocytes and erythrocyte ghosts at the level of micromolar (μmol dm−3) organotin per mg of membrane protein. Corresponding structures are assumed by Me2SnIV and Me3SnIV in the cytoplasm. Ethanolic Me2SnCl2 yielded distorted trans-octahedral species when reac…

chemistry.chemical_classificationBiomoleculechemistry.chemical_elementGeneral ChemistryQuadrupole splittingInorganic ChemistryMetalHydrolysisMembranechemistryCovalent bondvisual_artPolymer chemistryvisual_art.visual_art_mediumMoleculeTinApplied Organometallic Chemistry
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Oxidized respiratory molecules induced in vivo by nitrite in Pontodrilus littoralis (oligochaeta)

1992

Abstract 1. The in vivo effect of nitrite has been investigated in Pontodrilus littoralis. 2. Exposure of the animals at nitrite concentrations (0.05–0.1%) produced methaemoglobin and hemichromes. 3. Disappearance of oxidized forms was obtained when normal rearing conditions were restored. 4. Longer exposure to higher nitrite concentrations produced irreversible oxidized forms.

PharmacologyHemeproteinImmunologychemistry.chemical_elementNitrogenMethemoglobinchemistry.chemical_compoundBiochemistrychemistryIn vivoToxicityHemoglobinRespiratory systemNitriteComparative Biochemistry and Physiology Part C: Comparative Pharmacology
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