Postnatal predator exposure reduces fear and anxiety behaviors in adult mice

Poster; Predator cues are very efficient to induce fear in rodents but most studies use adult subjects and not pups. Nevertheless, a perinatal stress can have a significant effect on behavior and on physiology at adulthood. An early stress (foot shock, restraint, mother separation) is able to modulate behaviors later and the aim of this study was to examine if the synthetic predator odor 2,3,5-trimethylthiazoline (TMT) presented to neonates modifies fear and anxiety-related behaviors in adult female mice.