0000000000778645
AUTHOR
Federico Germini
showing 9 related works from this author
Predicting risk and outcomes for frail older adults: an umbrella review of frailty screening tools
2017
EXECUTIVE SUMMARY Background A scoping search identified systematic reviews on diagnostic accuracy and predictive ability of frailty measures in older adults. In most cases, research was confined to specific assessment measures related to a specific clinical model. Objectives To summarize the best available evidence from systematic reviews in relation to reliability, validity, diagnostic accuracy and predictive ability of frailty measures in older adults. Inclusion criteria Population Older adults aged 60 years or older recruited from community, primary care, long-term residential care and hospitals. Index test Available frailty measures in older adults. Reference test Cardiovascular Health…
Quality of reporting in abstracts of RCTs published in emergency medicine journals: a protocol for a systematic survey of the literature
2017
Introduction The quality of reporting of abstracts of randomised controlled trials (RCTs) in major general medical journals and in some category-specific journals was shown to be poor before the publication of the ConsolidatedStandards of ReportingTrials (CONSORT) extension for abstracts in 2008, and an improvement in the quality of reporting of abstracts was observed after its publication. The effect of the publication of the CONSORT extension for abstracts on the quality of reporting of RCTs in emergency medicine journals has not been studied. In this paper, we present the protocol of a systematic survey of the literature, aimed at assessing the quality of reporting in abstracts of RCTs p…
Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review
2018
OBJECTIVE: To summarize the best available evidence regarding the effectiveness of interventions for preventing frailty progression in older adults. INTRODUCTION: Frailty is an age-related state of decreased physiological reserves characterized by an increased risk of poor clinical outcomes. Evidence supporting the malleability of frailty, its prevention and treatment, has been presented. INCLUSION CRITERIA: The review considered studies on older adults aged 65 and over, explicitly identified as pre-frail or frail, who had been undergoing interventions focusing on the prevention of frailty progression. Participants selected on the basis of specific illness or with a terminal diagnosis were …
Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
AbstractBackgroundAge-related frailty is a multidimensional dynamic condition associated with adverse patient outcomes and high costs for health systems. Several interventions have been proposed to tackle frailty. This correspondence article describes the journey through the development of evidence- and consensus-based guidelines on interventions aimed at preventing, delaying or reversing frailty in the context of the FOCUS (Frailty Management Optimisation through EIP-AHA Commitments and Utilisation of Stakeholders Input) project (664367-FOCUS-HP-PJ-2014). The rationale, framework, processes and content of the guidelines are described.Main textThe guidelines were framed into four questions …
MOESM3 of Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
Additional file 3: Table S1. Table that describes the members of the FOCUS Guideline Panel and their role in the development of the guidelines.
MOESM4 of Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
Additional file 4. Example of the output of the voting process using the Evidence to Decision template, as received and processed by the guidelines technical team.
MOESM1 of Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
Additional file 1. Synthesis of quantitative evidence from the FOCUS systematic review [9], showing the effect of the interventions on frailty as an outcome, adapted from the typical GRADE Summary of Findings table structure, as offered to the guideline panellists.
MOESM5 of Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
Additional file 5. Detailed justification for the judgement upon each Evidence to Decision criterion, for each guideline.
MOESM2 of Interventions to prevent, delay or reverse frailty in older people: a journey towards clinical guidelines
2019
Additional file 2. Narrative synthesis of the effect of interventions on secondary outcomes, as offered to the guideline panellists.