0000000000785320

AUTHOR

Thomas M. Van Gulik

showing 2 related works from this author

REsect: Blinded assessment of amenability to potentially curative treatment of previously unresectable colorectal cancer liver metastases (CRC LM) af…

2017

3532 Background: Secondary resection and radiofrequency ablation (RFA) of primarily unresectable LM from CRC can prolong survival and cure some patients (pts). Effective downsizing treatments are needed but their impact on secondary amenability to surgery/RFA is difficult to evaluate objectively. The added value of SIRT is not well established. Methods: Baseline (BL) and follow-up (FU) imaging at best response for CRC pts treated with FOLFOX chemotherapy±bevacizumab (bev) (CT) vs. CT+SIRT in the phase III SIRFLOX RCT were reviewed by 3−5 expert HPB surgeons (from a panel of 15) for resectability of LM. Reviewers were blinded to each other and to all clinical information incl. time of imagi…

Cancer Researchmedicine.medical_specialtyChemotherapyRadiofrequency ablationbusiness.industryColorectal cancermedicine.medical_treatmentmedicine.diseaselaw.inventionResection03 medical and health sciences0302 clinical medicineOncologyRandomized controlled trialFOLFOXlawCurative treatment030220 oncology & carcinogenesisClinical informationmedicine030211 gastroenterology & hepatologyRadiologybusinessmedicine.drugJournal of Clinical Oncology
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The Southampton Consensus Guidelines for Laparoscopic Liver Surgery: From Indication to Implementation

2018

OBJECTIVE: The European Guidelines Meeting on Laparoscopic Liver Surgery was held in Southampton on February 10 and 11, 2017 with the aim of presenting and validating clinical practice guidelines for laparoscopic liver surgery.BACKGROUND: The exponential growth of laparoscopic liver surgery in recent years mandates the development of clinical practice guidelines to direct the speciality's continued safe progression and dissemination.METHODS: A unique approach to the development of clinical guidelines was adopted. Three well-validated methods were integrated: the Scottish Intercollegiate Guidelines Network methodology for the assessment of evidence and development of guideline statements; th…

Liver surgerymedicine.medical_specialtyDelphi TechniqueColorectal cancerindicationMEDLINE030230 surgeryCENTRAL VENOUS-PRESSUREINITIAL-EXPERIENCECOLORECTAL-CANCER03 medical and health sciences0302 clinical medicineSouthamptonOPEN LEFT HEMIHEPATECTOMYHEPATOCELLULAR-CARCINOMAmedicineHepatectomyHumansguidelinesproceduresimplementationPOSTEROSUPERIOR SEGMENTSbusiness.industryLiver DiseasesENERGY DEVICElaparoscopic liver surgerytechniquemedicine.disease2-STAGE HEPATECTOMYEnergy deviceclinical practiceSurgeryEuropeClinical PracticeGLISSONIAN APPROACHconsensus030220 oncology & carcinogenesisHepatocellular carcinomaLaparoscopySurgeryLEARNING-CURVEbusinesspatient selectionAnnals of surgery
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