0000000000791030

AUTHOR

Mathias Elsner

showing 2 related works from this author

Effects of indomethacin on muscarinic inhibition of endogenous noradrenaline release from rat isolated trachea

1993

The release of endogenous noradrenaline from rat isolated tracheae was evoked by electrical field stimulation (3 Hz, 540 pulses) in the presence of yohimbine, desipramine and tyrosine. The muscarine receptor agonist oxotremorine concentration-dependently inhibited the evoked release of noradrenaline by 95% at 1 μmol/l, EC50 values in two series of experiments 41 and 57 nmol/l, respectively. The effect of oxotremorine was antagonized by the non-selective muscarine receptor antagonist scopolamine (10–1000 nmol/l) in a manner suggesting a simple competitive interaction (slope of Schild plot −0.94; pA2 value 8.88). However, the M2 selective muscarine receptor antagonist methoctramine (0.1–10 μm…

medicine.medical_specialtymedicine.drug_classIndomethacinDiaminesIn Vitro TechniquesRats Sprague-DawleyNorepinephrinechemistry.chemical_compoundInternal medicineMuscarinic acetylcholine receptormedicineOxotremorineMethoctramineAnimalsPharmacologyMuscarineOxotremorineGeneral MedicineMuscarinic acetylcholine receptor M1Receptor antagonistReceptors MuscarinicPirenzepineRatsTracheaSchild regressionEndocrinologychemistryProstaglandinsFemalemedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Coronary artery bypass grafting in adult coronary artery disease due to suspected Kawasaki disease in childhood

2000

Development of coronary artery aneurysms is one typical complication of Kawasaki disease and can cause coronary artery disease even in early childhood. Information about course and outcome in adults is rare. Here, we present a 49-year-old man with serious three-vessel coronary artery disease and giant coronary artery aneurysms following suspected Kawasaki disease.

MalePulmonary and Respiratory MedicineSystemic diseasemedicine.medical_specialtyCoronary DiseaseMucocutaneous Lymph Node SyndromeCoronary artery diseaseAneurysmhemic and lymphatic diseasesInternal medicinemedicineHumanscardiovascular diseasesCoronary Artery BypassVascular diseasebusiness.industryCoronary AneurysmMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structurecardiovascular systemCardiologySurgeryKawasaki diseaseCardiology and Cardiovascular MedicinebusinessComplicationVasculitisArteryThe Annals of Thoracic Surgery
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