0000000000791576

AUTHOR

Christian Schlensak

showing 3 related works from this author

Intraoperative neuroprotective drugs without beneficial effects? Results of the German Registry for Acute Aortic Dissection Type A (GERAADA).

2013

OBJECTIVES: Cerebral protection during acute aortic dissection Type A (AADA) surgery may be affected by perfusion strategies and ischaemic protective drugs. METHODS: We analysed the impact of intraoperative barbiturate, steroid and mannitol use and adjunctive cerebral perfusion (CP), on 30-day mortality and new postoperative mortality-corrected permanent neurological dysfunction (PNDmc) in the German Registry for Acute Aortic Dissection Type A. RESULTS: Two thousand one hundred and thirty-seven AADA patients were registered over a 4-year period. The overall 30-day mortality was 16.9%, and the overall rate of PNDmc was 10.0%. A total of 48% of patients received no neuroprotective drugs (cont…

Pulmonary and Respiratory MedicineAortic archMalemedicine.drug_classOperative TimePostoperative ComplicationsRisk Factorsmedicine.arteryGermanymedicineHumansMannitolCerebral perfusion pressureCardiac Surgical ProceduresMortalityAgedAortic dissectionChi-Square DistributionIntraoperative Carebusiness.industryMortality rateGeneral MedicineOdds ratioMiddle Agedmedicine.diseaseAortic AneurysmAortic DissectionNeuroprotective AgentsBarbiturateAnesthesiaBarbituratesSurgeryFemaleSteroidsMannitolCardiology and Cardiovascular MedicinebusinessPerfusionmedicine.drugEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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Acute aortic dissection type A

2012

Abstract Background Acute aortic dissection type A (AADA) is a life-threatening vascular emergency. Clinical presentation ranges from pain related to the acute event, collapse due to aortic rupture or pericardial tamponade, or manifestations of organ or limb ischaemia. The purpose of this review was to clarify important clinical issues of AADA management, with a focus on diagnostic and therapeutic challenges. Methods Based on a MEDLINE search the latest literature on this topic was reviewed. Results from the German Registry for Acute Aortic Dissection Type A (GERAADA) are also described. Results Currently, the perioperative mortality rate of AADA is below 20 per cent, the rate of definitive…

Aortic archExtracorporeal Circulationmedicine.medical_specialtyAortic RupturePerioperative CareBrain IschemiaAortic aneurysmAneurysmHypothermia Inducedmedicine.arteryInternal medicinemedicineHumansAortic ruptureAortic dissectionbusiness.industryExtracorporeal circulationPrognosismedicine.diseaseAortic AneurysmSurgeryAortic DissectionAcute DiseaseCardiologySurgeryTamponadePresentation (obstetrics)businessBritish Journal of Surgery
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Acute Aortic Dissection Type A : Age-related Management and Outcomes Reported in the German Registry for Acute Aortic Dissection Type A (GERAADA) of …

2013

To determine the association between age and clinical presentation, management and surgical outcomes in a large contemporary, prospective cohort of patients with acute aortic dissection type A (AADA).AADA is one of the most life-threatening cardiovascular diseases, and delayed surgery or overly conservative management can result in sudden death.The perioperative and intraoperative conditions of 2137 patients prospectively reported to the multicenter German Registry for Acute Aortic Dissection Type A were analyzed.Of all patients with AADA, 640 (30%) were 70 years or older and 160 patients (7%) were younger than 40 years. The probability of aortic dissection extension to the supra-aortic ves…

AdultMalemedicine.medical_specialtyMedizinlaw.inventionYoung AdultAortic aneurysmSex FactorsAneurysmRandomized controlled triallawGermanymedicineHumansProspective StudiesRegistriesYoung adultProspective cohort studyAgedAortic dissectionAortic Aneurysm Thoracicbusiness.industryfungiAge FactorsMiddle AgedPrognosismedicine.diseaseSurgerySurvival RateAortic DissectionCardiothoracic surgeryAustriaFemaleSurgeryMorbiditybusinessVascular Surgical ProceduresSwitzerlandAortic Aneurysm AbdominalFollow-Up StudiesAbdominal surgery
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