0000000000794129

AUTHOR

Caputo E.

showing 2 related works from this author

Decline in the incidence of colorectal cancer and the associated mortality in young Italian adults

2020

Objective The incidence of colorectal cancer (CRC) declines among subjects aged 50 years and above. An opposite trend appears among younger adults. In Europe, data on CRC incidence among younger adults are lacking. We therefore aimed to analyse European trends in CRC incidence and mortality in subjects younger than 50 years. Design Data on age-related CRC incidence and mortality between 1990 and 2016 were retrieved from national and regional cancer registries. Trends were analysed by Joinpoint regression and expressed as annual percent change. Results We retrieved data on 143.7 million people aged 20–49 years from 20 European countries. Of them, 187 918 (0.13%) were diagnosed with CRC. On a…

0301 basic medicine2312ColonPopulationSocio-culturalecolorectal cancercolorectal cancer screening03 medical and health sciencesYoung Adult0302 clinical medicineEpidemiology of cancerMedicineHumans1506Risk factoreducationeducation.field_of_studycancer epidemiology Colorectal cancer colorectal cancer screeningbusiness.industryIncidence (epidemiology)Mortality ratescreeningIncidenceGastroenterologyCancermedicine.diseaseObesityAnnual Percent ChangeEurope030104 developmental biologyItaly030211 gastroenterology & hepatologyepidemiologybusinessColorectal NeoplasmsDemographycancer epidemiologySEER Program
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Synthetic indicator of the impact of colorectal cancer screening programmes on incidence rates

2020

ObjectiveThe impact of a screening programme on colorectal cancer (CRC) incidence in its target population depends on several variables, including coverage with invitations, participation rate, positivity rate of the screening test, compliance with an invitation to second-level assessment and endoscopists’ sensitivity. We propose a synthetic indicator that may account for all the variables influencing the potential impact of a screening programme on CRC incidence.DesignWe defined the ‘rate of advanced adenoma on the target population’ (AA-TAP) as the rate of patients who received a diagnosis of advanced adenoma within a screening programme, divided by the programme target population. We com…

AdenomaMaleColorectal cancercolorectal cancerTarget populationcolorectal cancer screeningNOScreening programmeSingle indicatormedicineHumansMass ScreeningNational levelEarly Detection of CancerAgedPotential impactbusiness.industryIncidenceIncidence (epidemiology)GastroenterologyColonoscopycolorectal cancer; colorectal cancer screening; Adenoma; Aged; Colonoscopy; Colorectal Neoplasms; Early Detection of Cancer; Female; Humans; Incidence; Italy; Male; Mass Screening; Middle Aged; Occult Blood; Patient Compliance; Program EvaluationMiddle Agedmedicine.diseaseItalyColorectal cancer screeningOccult BloodPatient ComplianceFemaleColorectal NeoplasmsbusinessProgram EvaluationDemographyGut
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