0000000000795528

AUTHOR

Andy Wc Man

0000-0002-4113-6479

showing 2 related works from this author

Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases

2020

Obesity is a major risk factor for most metabolic and cardiovascular disorders. Adipose tissue is an important endocrine organ that modulates metabolic and cardiovascular health by secreting signaling molecules. Oxidative stress is a common mechanism associated with metabolic and cardiovascular complications including obesity, type 2 diabetes, and hypertension. Oxidative stress can cause adipose tissue dysfunction. Accumulating data from both humans and experimental animal models suggest that adipose tissue function and oxidative stress have an innate connection with the intrinsic biological clock. Circadian clock orchestrates biological processes in adjusting to daily environmental changes…

0301 basic medicineCell signalingPhysiologyClinical BiochemistryCircadian clockAdipose tissueAdipokineReviewBioinformaticsmedicine.disease_causeBiochemistrysirtuin 103 medical and health sciences0302 clinical medicineAdipokinesclock genesMedicineoxidative stressCircadian rhythmbranched-chain amino acidsMolecular Biologyendothelial nitric oxide synthasebiologySirtuin 1business.industrylcsh:RM1-950Cell BiologyCLOCK030104 developmental biologylcsh:Therapeutics. Pharmacologybiology.proteinbusiness030217 neurology & neurosurgeryOxidative stressAntioxidants
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Resveratrol and the Interaction between Gut Microbiota and Arterial Remodelling

2020

Arterial remodelling refers to the alteration in the structure of blood vessel that contributes to the progression of hypertension and other cardiovascular complications. Arterial remodelling is orchestrated by the crosstalk between the endothelium and vascular smooth muscle cells (VSMC). Vascular inflammation participates in arterial remodelling. Resveratrol is a natural polyphenol that possesses anti-oxidant and anti-inflammatory properties and has beneficial effects in both the endothelium and VSMC. Resveratrol has been studied for the protective effects in arterial remodelling and gut microbiota, respectively. Gut microbiota plays a critical role in the immune system and inflammatory pr…

0301 basic medicineVascular smooth muscleEndotheliumMyocytes Smooth MusclePopulationlcsh:TX341-641InflammationReviewresveratrolVascular Remodeling030204 cardiovascular system & hematologyResveratrolGut floraPharmacologydigestive systemAntioxidantsMuscle Smooth VascularVascular remodelling in the embryo03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineAnimalsHumanseducationCell ProliferationNeointimal hyperplasiaeducation.field_of_studyNutrition and Dieteticsgut microbiotabiologybusiness.industryanti-oxidantSIRT1 arterial remodellingArteriesmedicine.diseasebiology.organism_classificationGastrointestinal Microbiome030104 developmental biologymedicine.anatomical_structurechemistryinflammationcardiovascular systemmedicine.symptombusinesslcsh:Nutrition. Foods and food supplyFood ScienceNutrients
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