0000000000796967

AUTHOR

Adriana Albini

showing 3 related works from this author

SV40 transformed fibroblasts recognize the same 140 kD fibronectin chemotactic fragment as non-transformed cells

1985

SV40-virus-transformed human embryonal fibroblasts show an enhanced chemotactic response to the glycoprotein fibronectin. However, they recognize the same chemotactic active region as non-transformed fibroblasts. The result suggests that an enhancement of chemotaxis by fibroblasts which have been transformed with Simian Virus 40 is due not to the utilization of further chemotactic domains in the molecule, but to an increased sensitivity of the cells to the chemoattractant.

virusesSimian virus 40BiologyVirus*Cell Transformation Viral Cells Cultured Chemotaxis/*drug effects Embryo Fibroblasts/physiology Fibronectins/*pharmacology Human Peptide Fragments/pharmacology Polyomavirus macacae/*physiologyCellular and Molecular NeurosciencemedicineHumansFibroblastMolecular BiologyCells CulturedPharmacologychemistry.chemical_classificationChemotaxisChemotaxisEmbryoCell BiologyFibroblastsCell Transformation ViralEmbryo MammalianVirologyPeptide FragmentsCell biologyFibronectinsSv40 virusFibronectinmedicine.anatomical_structurechemistryCell culturebiology.proteinMolecular MedicineGlycoprotein
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Prophylaxis of Non-communicable Diseases: Why fruits and vegetables may be better chemopreventive agents than dietary supplements based on isolated p…

2019

The World Health Organization (WHO) report from 2014 documented that non-communicable socalled civilization diseases such as cardiovascular disease, chronic respiratory diseases, cancer or type 2 diabetes are responsible for over 50% of all premature deaths in the world. Research carried out over the past 20 years has provided data suggesting that diet is an essential factor influencing the risk of development of these diseases. The increasing knowledge on chemopreventive properties of certain food ingredients, in particular, those of plant origin, opened the discussion on the possibility to use edible plants or their active components in the prevention of these chronic diseases. Health-pro…

Antioxidants; Bioactive phytochemicals; Cancer; Chemoprevention; Civilization diseases; Flavonoids; Food synergyantioxidantPhytochemicalsRespiratory Tract DiseasesActive componentsDiseaseChemopreventionWorld healthAntioxidants03 medical and health sciencesbioactive phytochemical0302 clinical medicineFunctional foodNeoplasmsVegetablesDrug DiscoveryHumansMedicinecivilization diseaseflavonoidNoncommunicable Diseases030304 developmental biologyCancer2. Zero hungerPharmacologyFlavonoids0303 health sciencesTraditional medicineFood synergyHuman organismbusiness.industryBioactive phytochemicalsDiet3. Good healthDiabetes Mellitus Type 2Cardiovascular DiseasesFruit030220 oncology & carcinogenesisFruits and vegetablesDietary SupplementsEdible plantsCivilization diseasesCritical assessmentbusiness
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SANIST: optimization of a technology for compound identification based on the European Union directive with applications in forensic, pharmaceutical …

2016

Electrospray Ionization and collision induced dissociation tandem mass spectrometry are usually employed to obtain compound identification through a mass spectra match. Different algorithms have been developed for this purpose (for example the nist match algorithm). These approaches compare the tandem mass spectra of the unknown analyte with the tandem mass spectra spectra of known compounds inserted in a database. The compounds are usually identified on the basis of spectral match value associated with a probability of recognition. However, this approach is not usually applied to multiple reaction monitoring transition spectra achieved by means of triple quadrupole apparatus, mainly due to…

BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICAForensic SciencebioinformaticDatabases Factualalgorithm; bioinformatic; compounds identification; database search; EU law; SpectroscopyChemistry PharmaceuticalForensic SciencesEU lawBayes TheoremBiomarkercompounds identificationdatabase searchAlgorithmTandem Mass SpectrometryHumansEuropean UnionSpectroscopyAlgorithmsBiomarkersFood AnalysisChromatography High Pressure Liquid
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