0000000000802260
AUTHOR
Claudia Sulitzky
Grafting of Molecularly Imprinted Polymer Films on Silica Supports Containing Surface-Bound Free Radical Initiators
Silica particles containing surface-bound free radical initiators have been used as supports for the grafting of thin films of molecularly imprinted polymers (MIPs). This technique offers a means of fine-tuning the layer thickness for improved kinetic properties or enhanced capacity in chromatographic or sensor applications. Thus prepared MIPs imprinted with l-phenylalanine anilide, have been characterized by FT-IR spectroscopy, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), elemental analysis, fluorescence microscopy, and scanning electron microscopy (SEM), providing evidence concerning the reproducibility in each step and the quantity and quality of the grafted…
Surface initiated molecularly imprinted polymer films: a new approach in chiral capillary electrochromatography
A new generation of imprinted composite particles was tested as capillary electrochromatography stationary phase. Silica particles characterised by a well defined particle size (10 µm diameter), shape and pore system (1000 A) were modified with an azoinitiator and subsequently used to graft molecularly imprinted polymers targeted to bind L-phenylalanine anilide. Fused silica capillaries were packed over a length corresponding to 8 cm, using a pneumatic amplification pump, and the stationary phase thus obtained was tested with respect to its electrochromatographic performance. The electroendosmotic flow mobility was evaluated with respect to both the different content of polymer on the silic…