0000000000803448

AUTHOR

M. Saiz

showing 2 related works from this author

Concentration-Dependent Protection by Ethanol Extract ofPropolis against &#947

2011

[EN] Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. We report for the first time a cytogenetic study to evaluate the radioprotective effect, in vitro, of propolis against radiation-induced chromosomal damage. Lymphocytes were cultured with increasing concentrations of ethanol extract of propolis (EEP), including 20, 40, 120, 250, 500, 750, 1000, and 2000 ¿g mL-1 and then exposed to 2 Gy ¿-rays. A significant and concentration-dependent decrease is observed in the frequency of chromoso…

Ionizing radiationRadiation protectionIn vitro studyDicentric chromosomeINGENIERIA NUCLEARPropolisArticleCell protectionCytogeneticsAntioxidant activityHuman cellFree radicalGamma radiationChromosome damageConcentration (parameters)LymphocyteChromosome aberrationRadiation injuryAlcoholLymphocyte cultureHumanPriority journal
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Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes

2010

Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. We report for the first time a cytogenetic study to evaluate the radioprotective effect,in vitro, of propolis against radiation-induced chromosomal damage. Lymphocytes were cultured with increasing concentrations of ethanol extract of propolis (EEP), including 20, 40, 120, 250, 500, 750, 1000, and 2000 μg mL−1and then exposed to 2 Gyγ-rays. A significant and concentration-dependent decrease is observed in the frequency of chromosome aberr…

EthanolAntioxidantArticle Subjectmedicine.drug_classLymphocytemedicine.medical_treatmentlcsh:Other systems of medicineBiologyPropolisPharmacologylcsh:RZ201-999ImmunostimulantChromosome aberrationIn vitroIonizing radiationchemistry.chemical_compoundmedicine.anatomical_structureComplementary and alternative medicinechemistryImmunologymedicineResearch ArticleEvidence-Based Complementary and Alternative Medicine
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