0000000000807187

AUTHOR

Olive Monique F Demgne

showing 2 related works from this author

Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects …

2021

Abstract Ethnopharmacological relevance Infections due to multidrug-resistant (MDR) bacteria constitute a real problem in the public health worldwide. Hypericum roeperianum Schimp. ex A. Rich (Hypericaceae) is used traditionally for treatment of various ailments such as abdominal pains, constipation, diarrhea, indigestion, nausea, and bacterial diseases. Aim of the study This study was aimed at investigating the antibacterial and antibiotic-modifying activity of the crude methanol extracts (HRB), ethyl-acetate soluble fraction (HRBa), residual material (HRBb), and 11 compounds from the bark of Hypericum roeperianum against multi-drug resistant (MDR) bacteria expressing active efflux pumps. …

medicine.drug_classTetracyclinePhytochemicalsAntibioticsMicrobial Sensitivity Tests03 medical and health sciences0302 clinical medicineDrug Resistance Multiple BacterialDrug Discoverymedicine030304 developmental biologyPharmacologyDoxycycline0303 health sciencesBacteriaTraditional medicinebiologyPlant ExtractsChemistryMembrane Transport ProteinsDrug Synergismbiology.organism_classificationAnti-Bacterial AgentsMultiple drug resistancePhytochemical030220 oncology & carcinogenesisPlant BarkEffluxAntibacterial activityHypericumBacteriamedicine.drugJournal of Ethnopharmacology
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A new polyketide from the bark of Hypericum roeperianum Schimp. (Hypericaceae)

2019

The isolation and spectroscopic data of a hitherto undescribed polyketide (1) from Hypericum roeperianum Schimp. (Hypericaceae) together with six known compounds (2–7) is herein reported. The struc...

010405 organic chemistryOrganic ChemistryPlant ScienceBiologyHypericaceaebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistryPolyketideHypericum roeperianumvisual_artBotanyvisual_art.visual_art_mediumBarkNatural Product Research
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