0000000000807217

AUTHOR

Johannes Breyer

showing 2 related works from this author

Accordance of Online Health Information on Prostate Cancer with the European Association of Urology Guidelines.

2017

<b><i>Background:</i></b> The internet is an emerging source of information for prostate cancer (PCa) patients. Since little is known about the quality of information on PCa provided online, we investigated its accordance to the latest European Association of Urology (EAU) guidelines. <b><i>Methods:</i></b> A total of 89 German web pages were included for analysis. A quality model classifying the provider of information and its expertise was introduced. Correctness of provided information was systematically compared to the EAU guidelines. <b><i>Results:</i></b> Information was provided by medical experts (41%), media (1…

Malemedicine.medical_specialtyAssociation (object-oriented programming)Urology030232 urology & nephrologyurologic and male genital diseasesAccess to Information03 medical and health sciencesProstate cancer0302 clinical medicinePatient Education as TopicGermanymedicineHumansSocieties MedicalInternetbusiness.industryInformation seekingInformation qualityProstatic Neoplasmsmedicine.diseaseInformation behaviorEuropeAccess to information030220 oncology & carcinogenesisFamily medicinePractice Guidelines as TopicThe InternetHealth informationNeoplasm Recurrence LocalbusinessUrologia internationalis
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Aquaporin 3 Expression Loss in Urothelial Carcinoma: Association with Tumor Invasion Depth, but not with Grading?

2017

We have previously provided molecular evidence of expression of aquaporin 3 (AQP3) in normal human urothelium and in UBC of various stages. Whereas former studies demonstrated that loss of AQP3 was associated with invasive and high-grade disease and worse progression-free and cancer-specific survival, this report investigates the expression of AQP3 in associated CIS. Contrary to what we had expected, all CIS specimens were shown to exhibit strong AQP3 expression, suggesting loss of AQP3 in UBC is primarily associated with the ability of tumor cells for invasion but not with grading as sign of dedifferentiation.

Invasion depthPathologymedicine.medical_specialtyUrologyCarcinoma in situShort CommunicationBladder030232 urology & nephrologycarcinoma in situMolecular evidenceBiologymedicine.disease03 medical and health sciences0302 clinical medicineOncologyAquaporin 3030220 oncology & carcinogenesisimmunohistochemistrymedicineImmunohistochemistryUrotheliumaquaporin 3Grading (tumors)urothelial carcinomaUrothelial carcinomaBladder Cancer (Amsterdam, Netherlands)
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